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Multimodality treatment of primary cardiac angiosarcoma: A systematic literature review

期刊: CANCER TREATMENT REVIEWS, 2023; 120 ()

Background: Primary cardiac angiosarcoma (PCA) is the most prevalent histological type of cardiac sarcoma but its rarity poses a challenge for standar......

Comparison of HER2-zero and HER2-low in terms of clinicopathological factors and survival in early-stage breast cancer: A systematic review and meta-analysis

期刊: CANCER TREATMENT REVIEWS, 2023; 115 ()

Background: The prognostic differences between HER2-zero and HER2-low breast cancer (BC) remain unclear. Purpose of this meta-analysis is to investiga......

European expert panel consensus on the clinical management of BRAFV600E-mutant metastatic colorectal cancer

期刊: CANCER TREATMENT REVIEWS, 2023; 115 ()

Metastatic colorectal cancer (mCRC) is a heterogenous disease caused by various genetic alterations. The BRAFV600E mutation occurs in approximately 8-......

Risk of thromboembolic events in patients with metastatic solid tumors treated with PARP inhibitors: A systematic review and meta-analysis of phase 3 randomized controlled trials

期刊: CANCER TREATMENT REVIEWS, 2023; 119 ()

Background and scope: Poly(ADP-ribose) polymerase inhibitors (PARPi) have revolutionized cancer treatment in recent years. These drugs present a favor......

Regulatory T cells in gastric cancer: Key controllers from pathogenesis to therapy

期刊: CANCER TREATMENT REVIEWS, 2023; 120 ()

Gastric cancer (GC) is a highly aggressive malignancy that remains a significant contributor to cancer-related mortality worldwide, despite a decline ......

Secondary prevention and treatment innovation of early stage non-small cell lung cancer: Impact on diagnostic-therapeutic pathway from a multidisciplinary perspective

期刊: CANCER TREATMENT REVIEWS, 2023; 116 ()

Lung cancer (LC) is the leading cause of cancer-related death worldwide, mostly because the lack of a screening program so far. Although smoking cessa......

Stereotactic body radiation therapy in unresectable stage III non-small cell lung cancer: A systematic review

期刊: CANCER TREATMENT REVIEWS, 2023; 118 ()

In unresectable stage III non-small cell lung cancer (NSCLC), the standard of care for most fit patients is con-current chemotherapy with normofractio......

Liquid biopsy after resection of pancreatic adenocarcinoma and its relation to oncological outcomes. Systematic review and meta-analysis

期刊: CANCER TREATMENT REVIEWS, 2023; 120 ()

Background: It has been hypothesised that manipulation during surgery releases tumoral components into circulation. We investigate the effect of surge......

Tucatinib's journey from clinical development to clinical practice: New horizons for HER2-positive metastatic disease and promising prospects for brain metastatic spread

期刊: CANCER TREATMENT REVIEWS, 2023; 120 ()

Approximately 20% of breast cancers (BCs) overexpress human epidermal growth factor receptor 2 (HER2), a transmembrane glycoprotein with tyrosine kina......

Theranostic biomarkers and PARP-inhibitors effectiveness in patients with non-BRCA associated homologous recombination deficient tumors: Still looking through a dirty glass window?

期刊: CANCER TREATMENT REVIEWS, 2023; 121 ()

Breast cancer susceptibility gene 1 (BRCA1) and breast cancer susceptibility gene 2 (BRCA2) deleterious variants were the first and, still today, the ......

TROP-2 directed antibody-drug conjugates (ADCs): The revolution of smart drug delivery in advanced non-small cell lung cancer (NSCLC)

期刊: CANCER TREATMENT REVIEWS, 2023; 118 ()

Background: Antibody drug conjugates (ADCs) represent a revolutionary drug class in cancer therapy, combining the precision of targeted therapy with t......

Sex dimorphism and cancer immunotherapy: May pregnancy solve the puzzle?

期刊: CANCER TREATMENT REVIEWS, 2023; 121 ()

In the immunoncology era, growing evidence has shown a clear sex dimorphism in antitumor immune response with a potential impact on outcomes upon immu......

Strategies for improving detection of circulating tumor DNA using next generation sequencing

期刊: CANCER TREATMENT REVIEWS, 2023; 119 ()

Cancer has become a global health issue and liquid biopsy has emerged as a non-invasive tool for various applications. In cancer, circulating tumor DN......

Local control strategies for management of NSCLC with oligoprogressive disease

期刊: CANCER TREATMENT REVIEWS, 2023; 120 ()

Progresses of systemic treatments in advanced non-small cell lung cancer (NSCLC), such as immune checkpoint blockers (ICB) and targeted therapies, led......

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