期刊： SCIENCE IMMUNOLOGY, 2020; 5 (44)
We investigated the molecular and cellular basis of severe combined immunodeficiency (SCID) in six patients with otofaciocervical syndrome type 2 who ......
期刊： SCIENCE IMMUNOLOGY, 2020; 5 (44)
Although mammalian secretory immunoglobulin A (sIgA) targets mucosal pathogens for elimination, its interaction with the microbiota also enables comme......
期刊： SCIENCE IMMUNOLOGY, 2020; 5 (44)
B cells undergo two types of genomic alterations to increase antibody diversity: introduction of point mutations into immunoglobulin heavy- and light-......
期刊： SCIENCE IMMUNOLOGY, 2020; 5 (46)
Intestinal mononuclear phagocytes (MPs) are composed of heterogeneous dendritic cell (DC) and macrophage subsets necessary for the initiation of immun......
期刊： SCIENCE IMMUNOLOGY, 2020; 5 (47)
Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA are frequently observed in COVID-19. However, it is unclear whether SARS-CoV-2 replicat......
期刊： SCIENCE IMMUNOLOGY, 2020; 5 (47)
Serological testing for SARS-CoV-2 has enormous potential to contribute to COVID-19 pandemic response efforts. However, the required performance chara......
期刊： SCIENCE IMMUNOLOGY, 2020; 5 (54)
Deficiency in interleukin-36R (IL-36R) antagonist caused by loss-of-function mutations in IL-36RN leads to DITRA (deficiency of IL-36 receptor antagon......
