筛选条件 共查询到18条结果
排序方式
Fulminant corticobasal degeneration: a distinct variant with predominant neuronal tau aggregates

期刊: ACTA NEUROPATHOLOGICA, 2020; 139 (4)

Corticobasal degeneration typically progresses gradually over 5-7 years from onset till death. Fulminant corticobasal degeneration cases with a rapidl......

Overlapping genetic architecture between Parkinson disease and melanoma

期刊: ACTA NEUROPATHOLOGICA, 2020; 139 (2)

Epidemiologic studies have reported inconsistent results regarding an association between Parkinson disease (PD) and cutaneous melanoma (melanoma). Id......

TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis

期刊: ACTA NEUROPATHOLOGICA, 2020; 140 (4)

Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease of the central nervous system (CNS) triggered by autoimmune m......

APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer's disease

期刊: ACTA NEUROPATHOLOGICA, 2020; 140 (4)

Beta-amyloid deposition is a defining feature of Alzheimer's disease (AD). How genetic risk factors, likeAPOEandTREM2, intersect with cellular respons......

The KBTBD6/7-DRD2 axis regulates pituitary adenoma sensitivity to dopamine agonist treatment

期刊: ACTA NEUROPATHOLOGICA, 2020; 140 (3)

Pituitary adenoma (PA) is one of the most common intracranial tumors, and approximately 40% of all PAs are prolactinomas. Dopamine agonists (DAs), suc......

TDP-43 transports ribosomal protein mRNA to regulate axonal local translation in neuronal axons

期刊: ACTA NEUROPATHOLOGICA, 2020; 140 (5)

Mislocalization and abnormal deposition of TDP-43 into the cytoplasm (TDP-43 proteinopathy) is a hallmark in neurons of amyotrophic lateral sclerosis ......

The TMEM106B FTLD-protective variant, rs1990621, is also associated with increased neuronal proportion

期刊: ACTA NEUROPATHOLOGICA, 2020; 139 (1)

Apart from amyloid beta deposition and tau neurofibrillary tangles, Alzheimer's disease (AD) is a neurodegenerative disorder characterized by neuronal......

Molecular profiling of tumors of the brainstem by sequencing of CSF-derived circulating tumor DNA

期刊: ACTA NEUROPATHOLOGICA, 2019; 137 (2)

Brainstem gliomas are molecularly heterogeneous diseases, many of which are difficult to safely surgically resect and have limited treatment options d......

JIF:18.17

Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains

期刊: ACTA NEUROPATHOLOGICA, 2019; 137 (6)

The cytoplasmic accumulation of the nuclear TAR DNA-binding protein 43 (TDP-43) is a pathologic hallmark in amyotrophic lateral sclerosis, frontotempo......

JIF:18.17

Pediatric low-grade gliomas can be molecularly stratified for risk

期刊: ACTA NEUROPATHOLOGICA, 2018; 136 (4)

Pediatric low-grade gliomas (PLGGs) consist of a number of entities with overlapping histological features. PLGGs have much better prognosis than the ......

JIF:18.17

Targeting pericytes for therapeutic approaches to neurological disorders

期刊: ACTA NEUROPATHOLOGICA, 2018; 136 (4)

Manycentral nervous system diseases currently lack effective treatment and are often associated with defects in microvascular function, including a fa......

JIF:18.17

共18条页码: 1/2页15条/页
打开APP