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Value of serum tumor markers for predicting EGFR mutations and positive ALK expression in 1089 Chinese non-small-cell lung cancer patients: A retrospective analysis

期刊: EUROPEAN JOURNAL OF CANCER, 2020; 124 ()

Purpose: The role of serum tumor markers (STMs) in the modern management of epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (AL......

Poor clinical outcomes of intratumoral dendritic cellespecific intercellular adhesion molecule 3-grabbing non-integrinepositive macrophages associated with immune evasion in gastric cancer

期刊: EUROPEAN JOURNAL OF CANCER, 2020; 128 ()

Aim: Tumour-associated macrophages (TAMs) are prominent immune cells infiltrating in solid tumours with phenotypic and functional heterogeneity. Howev......

Multimorbidity and short-term overall mortality among colorectal cancer patients in Spain: A population-based cohort study

期刊: EUROPEAN JOURNAL OF CANCER, 2020; 129 ()

Background: Numerous studies have analysed the effect of comorbidity on cancer outcomes, but evidence on the association between multimorbidity and sh......

Safety and clinical efficacy of toripalimab, a PD-1 mAb, in patients with advanced or recurrent malignancies in a phase I study

期刊: EUROPEAN JOURNAL OF CANCER, 2020; 130 ()

Purpose: This is a first-in-human phase I study investigating the safety and efficacy of toripalimab, a humanized monoclonal antibody against the prog......

Effect of apatinib plus neoadjuvant chemotherapy followed by resection on pathologic response in patients with locally advanced gastric adenocarcinoma: A single-arm, open-label, phase II trial

期刊: EUROPEAN JOURNAL OF CANCER, 2020; 130 ()

Background: The evidence of combining neoadjuvant chemotherapy with targeted therapy for patients with locally advanced gastric cancer is inadequate. ......

Hepatic arterial infusion of oxaliplatin plus raltitrexed in patients with intermediate and advanced stage hepatocellular carcinoma: A phase II, single-arm, prospective study

期刊: EUROPEAN JOURNAL OF CANCER, 2020; 134 ()

Purpose: To investigate the efficacy and safety of hepatic arterial infusion (HAI) of oxaliplatin plus raltitrexed in patients with intermediate stage......

Preclinical profile and phase I clinical trial of a novel androgen receptor antagonist GT0918 in castration-resistant prostate cancer

期刊: EUROPEAN JOURNAL OF CANCER, 2020; 134 ()

Purpose: We conducted preclinical experiments and phase I clinical trial to investigate the safety, pharmacokinetics (PK) and antitumour effects of GT......

Lymphoblastic predominance of blastic phase in children with chronic myeloid leukaemia treated with imatinib: A report from the I-CML-Ped Study

期刊: EUROPEAN JOURNAL OF CANCER, 2020; 137 ()

Background: Chronic myeloid leukaemia (CML) is a rare disease in children. The frequency and outcome of children evolving to accelerated phase (AP) or......

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