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Using machine learning method to identify MYLK as a novel marker to predict biochemical recurrence in prostate cancer

期刊: BIOMARKERS IN MEDICINE, 2021; 15 (1)

Aim: This study aims to identify novel marker to predict biochemical recurrence (BCR) in prostate cancer patients after radical prostatectomy with neg......

Prognostic significance of eight immune-related genes on survival in patients with lung squamous cell carcinoma

期刊: BIOMARKERS IN MEDICINE, 2021; 15 (4)

Aim: To build a valid prognostic model based on immune-related genes for lung squamous cell carcinoma (LUSC). Materials & methods: Differential ex......

Establishment of reference intervals of ten commonly used clinical chemistry analytes: a real-world study in China

期刊: BIOMARKERS IN MEDICINE, 2021; 15 (11)

Aim: This real-world study was aimed at establishing reference intervals (RIs) of ten commonly used clinical chemistry analytes (total cholesterol, tr......

Identification of potential genomic biomarkers for Parkinson's disease using data pooling of gene expression microarrays

期刊: BIOMARKERS IN MEDICINE, 2021; 15 (8)

Aim: In this study, we aimed to identify potential diagnostic biomarkers Parkinson's disease (PD) by exploring microarray gene expression data of PD p......

Cleavage and polyadenylation-specific factor 3 induces cell cycle arrest via PI3K/Akt/GSK-3 beta signaling pathways and predicts a negative prognosis in hepatocellular carcinoma

期刊: BIOMARKERS IN MEDICINE, 2021; 15 (5)

Background: Recent studies have shown that cleavage and polyadenylation-specific factor 3 (CPSF3) is a promising antitumor therapeutic target, but its......

Decreased expression of ARID1A invasively downregulates the expression of ribosomal proteins in hepatocellular carcinoma

期刊: BIOMARKERS IN MEDICINE, 2021; 15 (7)

Background: There was increasing evidence showing that ARID1A alterations correlated with higher tumor mutational burden, but there were limited studi......

The relationship between serum lactate dehydrogenase level and mortality in critically ill patients

期刊: BIOMARKERS IN MEDICINE, 2021; 15 (8)

Background: To assess the association between serum lactate dehydrogenase (LDH) levels and mortality in intensive care unit patients. Materials & ......

AKP and GGT level can provide early prediction of first-line treatment efficacy in colorectal cancer patients with hepatic metastases

期刊: BIOMARKERS IN MEDICINE, 2021; 15 (10)

Aim: It is important to early evaluate or predict the efficacy to avoid ineffective treatment for most colorectal cancer (CRC) patients with liver met......

Association between the rs3733846 in the flanking region of miR-143/145 and risk of cervical squamous cell carcinoma

期刊: BIOMARKERS IN MEDICINE, 2021; 15 (11)

Aim: To investigate the effect of rs3733846 in the flanking region of miR-143/145 on susceptibility to cervical squamous cell carcinoma (CSCC). Materi......

A novel three-long noncoding RNA risk score system for the prognostic prediction of triple-negative breast cancer

期刊: BIOMARKERS IN MEDICINE, 2021; 15 (1)

Background: Triple-negative breast cancer (TNBC) is characterized by fast tumor increase, rapid recurrence and natural metastasis. We aimed to identif......

Identification of an immune-related long noncoding RNA signature that predicts prognosis in breast cancer patients

期刊: BIOMARKERS IN MEDICINE, 2021; 15 (3)

Aim: The purpose of this study was to identify an immune-related long noncoding RNA (lncRNA) signature that predicts the prognosis of breast cancer. M......

Prognostic and clinicopathological role of long noncoding RNA NORAD in various cancers: a meta-analysis

期刊: BIOMARKERS IN MEDICINE, 2021; 15 (6)

Aim: Long noncoding RNA (lncRNA) noncoding RNA activated by DNA damage (NORAD) is widely investigated in different tumors. Our meta-analysis intends t......

CARD11 is a novel target of miR-181b that is upregulated in chronic lymphocytic leukemia

期刊: BIOMARKERS IN MEDICINE, 2021; 15 (9)

Aim: To investigate the targets of miR-181b in patients with chronic lymphocytic leukemia (CLL). Materials & methods: The bioinformatic softwares ......

Sex-biased DNA methylation in papillary thyroid cancer

期刊: BIOMARKERS IN MEDICINE, 2021; 15 (2)

Background: Women have a higher risk of developing papillary thyroid cancer (PTC) than men. DNA methylation is known to differ between men and women. ......

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