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T follicular helper cells improve the response of patients with chronic hepatitis B to interferon by promoting HBsAb production

期刊: JOURNAL OF GASTROENTEROLOGY, 2022; 57 (1)

Background and aims Hepatitis B surface antigen (HBsAg) seroconversion is considered the optimal outcome of the treatment of chronic hepatitis B virus......

JIF:6.102

LncRNA n339260 functions in hepatocellular carcinoma progression via regulation of miRNA30e-5p/TP53INP1 expression

期刊: JOURNAL OF GASTROENTEROLOGY, 2022; 57 (10)

Background Currently, the molecular mechanism of the interaction between lncRNAs and microRNAs (miRNAs) and the target of miRNAs in tumor vasculogenic......

JIF:6.102

Sorafenib as adjuvant therapy following radiofrequency ablation for recurrent hepatocellular carcinoma within Milan criteria: a multicenter analysis

期刊: JOURNAL OF GASTROENTEROLOGY, 2022; 57 (9)

Background Radiofrequency ablation (RFA) is considered as a convenient treatment with mild damage in treating recurrent hepatocellular carcinoma (RHCC......

JIF:6.102

Kindlin-2-miR-1258-TCF4 feedback loop promotes hepatocellular carcinoma invasion and metastasis

期刊: JOURNAL OF GASTROENTEROLOGY, 2022; 57 (5)

Background Upregulated Kindlin-2 expression in hepatocellular carcinoma (HCC) correlates with metastasis and poor prognosis. In this study, we investi......

JIF:6.102

The clinical outcome from early versus delayed minimally invasive intervention for infected pancreatic necrosis: a systematic review and meta-analysis

期刊: JOURNAL OF GASTROENTEROLOGY, 2022; 57 (6)

Background While the management of infected pancreatic necrosis (IPN) has evolved in the last two decades with the adoption of minimally invasive inte......

JIF:6.102

Tenofovir vs. entecavir on prognosis of hepatitis B virus-related hepatocellular carcinoma after curative resection

期刊: JOURNAL OF GASTROENTEROLOGY, 2022; 57 (3)

Background Entecavir (ETV) and tenofovir disoproxil fumarate (TDF) are recommended as first-line choices regarding the treatment of chronic hepatits B......

JIF:6.102

CCL19 enhances CD8(+) T-cell responses and accelerates HBV clearance

期刊: JOURNAL OF GASTROENTEROLOGY, 2021; 56 (8)

Background Chemokine (C-C motif) ligand 19 (CCL19) is a leukocyte chemoattractant that plays a crucial role in cell trafficking and leukocyte activati......

STING and liver disease

期刊: JOURNAL OF GASTROENTEROLOGY, 2021; 56 (8)

STING (stimulator of interferon genes) also known as transmembrane protein 173 (TMEM173) is a cytoplasmic DNA sensor which can be activated by the ups......

Comprehensive aptamer-based screen of 1317 proteins uncovers improved stool protein markers of colorectal cancer

期刊: JOURNAL OF GASTROENTEROLOGY, 2021; 56 (7)

Background To screen and validate novel stool protein biomarkers of colorectal cancer (CRC). Methods A novel aptamer-based screen of 1317 proteins was......

HBeAg-positive patients with HBsAg < 100 IU/mL and negative HBV RNA have lower risk of virological relapse after nucleos(t)ide analogues cessation

期刊: JOURNAL OF GASTROENTEROLOGY, 2021; 56 (9)

Background Nucleos(t)ide analogues (NAs) cessation is not widely practiced and remains a controversial, but highly relevant subject in patients infect......

Safety and efficacy of lenvatinib by starting dose based on body weight in patients with unresectable hepatocellular carcinoma in REFLECT

期刊: JOURNAL OF GASTROENTEROLOGY, 2021; 56 (6)

Background REFLECT was an open-label, phase 3 study comparing the efficacy and safety of lenvatinib versus sorafenib in patients with unresectable hep......

Residual HBV DNA and pgRNA viraemia is associated with hepatocellular carcinoma in chronic hepatitis B patients on antiviral therapy

期刊: JOURNAL OF GASTROENTEROLOGY, ; ()

Background We aimed to assess whether residual hepatitis B virus (HBV) viraemia is associated with HCC development. Methods This is a case-control stu......

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