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The epidemiological landscape of multiple myeloma: a global cancer registry estimate of disease burden, risk factors, and temporal trends

期刊: LANCET HAEMATOLOGY, 2022; 9 (9)

Background Multiple myeloma accounted for 176 404 (14%) of 1 278 362 the incidence cases leukaemia, lymphoma, and multiple myeloma in 2020. Identifyin......

Venetoclax plus 3+7 daunorubicin and cytarabine chemotherapy as first-line treatment for adults with acute myeloid leukaemia: a multicentre, single-arm, phase 2 trial

期刊: LANCET HAEMATOLOGY, 2022; 9 (6)

Background Adults with acute myeloid leukaemia have unsatisfactory dinical outcomes and rates of complete remission. Venetodax combined with azacytidi......

Dexamethasone plus oseltamivir versus dexamethasone in treatment-naive primary immune thrombocytopenia: a multicentre, randomised, open-label, phase 2 trial

期刊: LANCET HAEMATOLOGY, 2021; 8 (4)

Background Primary immune thrombocytopenia is an autoimmune bleeding disorder. Preclinical reports suggest that the sialidase inhibitor oseltamivir in......

Comparison of international societal guidelines for the diagnosis of suspected pulmonary embolism during pregnancy

期刊: LANCET HAEMATOLOGY, 2020; 7 (3)

Pregnancy-associated pulmonary embolism is one of the leading causes of maternal mortality. Diagnosis of pulmonary embolism in pregnancy is challengin......

Subcutaneous versus intravenous daratumumab in patients with relapsed or refractory multiple myeloma (COLUMBA): a multicentre, open-label, non-inferiority, randomised, phase 3 trial

期刊: LANCET HAEMATOLOGY, 2020; 7 (5)

Background Intravenous daratumumab for treatment of patients with multiple myeloma involves a lengthy infusion that affects quality of life, and infus......

Implementing newborn screening for sickle cell disease as part of immunisation programmes in Nigeria: a feasibility study

期刊: LANCET HAEMATOLOGY, 2020; 7 (7)

Background Sickle cell disease is highly prevalent in sub-Saharan Africa, where it accounts for substantial morbidity and mortality. Newborn screening......

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