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Genetic polymorphism of clopidogrel metabolism related gene CYP2C19 gene in Chinese from Foshan area of Guangdong Province

期刊: HEMATOLOGY, 2022; 27 (1)

Background: The CYP2C19 gene is highly polymorphic, and CYP2C19 is involved in the broad interindividual variability of the clinical efficacy of certa......

JIF:1.732

Circ_0003489 facilitates multiple myeloma progression by targeting miR-433-3p/PBX3 axis

期刊: HEMATOLOGY, 2022; 27 (1)

Background: Multiple myeloma (MM) is a relatively common hematologic tumor, and the study of non-coding RNAs in MM is gradually increasing. Our study ......

JIF:1.732

Establishment of a prediction model for disease progression within one year in newly diagnosed multiple myeloma patients

期刊: HEMATOLOGY, 2022; 27 (1)

Purpose Multiple myeloma is still an incurable disease In the past decade, with the continuous progress of treatment methods, the progression-free sur......

JIF:1.732

CircNFIX knockdown inhibited AML tumorigenicity by the miR-876-3p/TRIM31 axis

期刊: HEMATOLOGY, 2022; 27 (1)

Background Acute myeloid leukemia (AML) is one of the most common malignant myeloid diseases in adults with a dismal prognosis. We aimed to explore th......

JIF:1.732

Clinical and molecular characteristics of acute myeloid leukemia with MPL mutation

期刊: HEMATOLOGY, 2022; 27 (1)

Objectives The current study aimed to explore the incidence of MPL mutations and the clinical and molecular characteristics of AML with MPL mutation. ......

JIF:1.732

SPRY1 promotes cell proliferation and inhibits apoptosis by activating Hedgehog pathway in acute myeloid leukemia

期刊: HEMATOLOGY, 2022; 27 (1)

Objective The aim of this study was to determine the biological function of Sprouty 1 (SPRY1) on acute myeloid leukemia (AML), and to investigate the ......

JIF:1.732

The prognostic effect on childhood acute lymphoblastic leukemia of CD34(+)CD38(-) expressed in leukemia cells

期刊: HEMATOLOGY, 2022; 27 (1)

Objective: Acute lymphoblastic leukemia is the most common malignant disease in children. CD34 and CD38 are expressed in both normal and leukemia cell......

JIF:1.732

Value of 3.0T MRI T2 mapping combined with SWI for the assessment of early lesions in hemophilic arthropathy

期刊: HEMATOLOGY, 2022; 27 (1)

Purpose To explore the value of magnetic resonance imaging (MRI) T2 mapping combined with susceptibility-weighted imaging (SWI) in detecting early car......

JIF:1.732

Application of third-generation sequencing for genetic testing of thalassemia in Guizhou Province, Southwest China

期刊: HEMATOLOGY, 2022; 27 (1)

Objectives: To explore the application of third-generation sequencing (TGS) for genetic diagnosis and prenatal genetic screening of thalassemia genes.......

JIF:1.732

Monoclonal antibodies: new chance in the management of B-cell acute lymphoblastic leukemia

期刊: HEMATOLOGY, 2022; 27 (1)

Objectives: This review aims to see the progress of several clinically-used monoclonal antibodies in treating ALL patients and how they improved patie......

JIF:1.732

Clonal heterogeneity of polymorphic B-cell lymphoproliferative disease, EBV-positive, iatrogenic/immune senescence: implications on pathogenesis and treatment

期刊: HEMATOLOGY, 2022; 27 (1)

Background Epstein Barr virus positive (EBV+) immunodeficiency-associated lymphoproliferative disorders (IA-LPD) are heterogeneous diseases with varia......

JIF:1.732

Identification of a rare compound heterozygous hemoglobin variant beta 0-thal [beta 17(A14) Lys>Stop, HBB: c.52A>T] and Hb J-Lome [beta 59(E3) Lys>Asn, HBB: c.180G>C]

期刊: HEMATOLOGY, 2022; 27 (1)

Background HbA1c is the validated biomarker for glycemic management in diabetic individuals. Here, we report a compound heterozygote for beta(0)-thal ......

JIF:1.732

The -alpha(3.7III) subtype of alpha(+)-thalassemia was identified in China

期刊: HEMATOLOGY, 2022; 27 (1)

Objective: The 3.7 kb deletion (-alpha(3.7)) in the alpha-globin cluster, which characterizes alpha(+)-thalassemia, has been reported to have a carrie......

JIF:1.732

Tyrosine kinase inhibitors and reduced-dose chemotherapy for adult Philadelphia chromosome-positive acute lymphoblastic leukemia

期刊: HEMATOLOGY, 2022; 27 (1)

Objectives: To compare the outcomes of tyrosine kinase inhibitors (TKIs) in combination with reduced-dose chemotherapy with those of standard inductio......

JIF:1.732

The effect of marital status on the survival of patients with multiple myeloma

期刊: HEMATOLOGY, 2022; 27 (1)

Objectives To investigate the impact of marriage on multiple myeloma (MM) survival, and the role of factors such as age, sex, and income in this relat......

JIF:1.732

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