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An ortholog of the Vasa intronic gene is required for small RNA-mediated translation repression in Chlamydomonas reinhardtii

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

Small RNAs (sRNAs) associate with Argonaute (AGO) proteins in effector complexes, termed RNA-induced silencing complexes (RISCs), which regulate compl......

OsmiR528 regulates rice-pollen intine formation by targeting an uclacyanin to influence flavonoid metabolismz

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

The intine, the inner layer of the pollen wall, is essential for the normal development and germination of pollen. However, the composition and develo......

Dorsoventral decoupling of Hox gene expression underpins the diversification of molluscs

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

In contrast to the Hox genes in arthropods and vertebrates, those in molluscs show diverse expression patterns with differences reported among lineage......

Long-term effects of cultural filtering on megafauna species distributions across China

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

Human activities currently play a dominant role in shaping and eroding Earth's biodiversity, but the historical dynamics leading to this situation are......

Enhanced expression of beta cell Ca(v)3.1 channels impairs insulin release and glucose homeostasis

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

Voltage-gated calcium 3.1 (Ca(v)3.1) channels are absent in healthy mouse beta cells and mediate minor T-type Ca2+ currents in healthy rat and human b......

Two closed ATP- and ADP-dependent conformations in yeast Hsp90 chaperone detected by Mn(II) EPR spectroscopic techniques

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

Hsp90 plays a central role in cell homeostasis by assisting folding and maturation of a large variety of clients. It is a homo-dimer, which functions ......

Uncovering the functional residues of Arabidopsis isoprenoid biosynthesis enzyme HDS

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

The methylerythritol phosphate (MEP) pathway is responsible for producing isoprenoids, metabolites with essential functions in the bacterial kingdom a......

Reversible phosphorylation of Rpn1 regulates 26S proteasome assembly and function

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

The fundamental importance of the 26S proteasome in health and disease suggests that its function must be finely controlled, and yet our knowledge abo......

In situ self-assembling Au-DNA complexes for targeted cancer bioimaging and inhibition

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

Cancer remains one of the most challenging diseases to treat. For accurate cancer diagnosis and targeted therapy, it is important to assess the locali......

An R2R3 MYB transcription factor confers brown planthopper resistance by regulating the phenylalanine ammonia-lyase pathway in rice

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

Brown planthopper (BPH) is one of the most destructive insects affecting rice (Oryza sativa L.) production. Phenylalanine ammonia-lyase (PAL) is a key......

Spectroscopic fingerprint of chiral Majorana modes at the edge of a quantum anomalous Hall insulator/superconductor heterostructure

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

With the recent discovery of the quantum anomalous Hall insulator (QAHI), which exhibits the conductive quantum Hall edge states without external magn......

Studies on the origin of the interfacial superconductivity of Sb2Te3/Fe1+yTe heterostructures

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

The recent discovery of the interfacial superconductivity (SC) of the Bi2Te3/Fe1+yTe heterostructure has attracted extensive studies due to its potent......

Biodegradable nanofiber-based piezoelectric transducer

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

Piezoelectric materials, a type of "smart" material that generates electricity while deforming and vice versa, have been used extensively for many imp......

Evidence for the stability of ultrahydrous stishovite in Earth's lower mantle

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

The distribution and transportation of water in Earth's interior depends on the stability of water-bearing phases. The transition zone in Earth's mant......

Complexity-based approach for El Nino magnitude forecasting before the spring predictability barrier

期刊: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020; 117 (1)

The El Nino Southern Oscillation (ENSO) is one of the most prominent interannual climate phenomena. Early and reliable ENSO forecasting remains a cruc......

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