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Prognostic value and characterization of NTRK1 variation by fluorescence in situ hybridization in esophageal squamous cell carcinoma

期刊: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021; 147 (10)

Purpose Rearrangement of the neurotrophic tyrosine kinase receptor (NTRK) 1 gene is a target of tropomyosin receptor kinase A (TRKA) inhibitors, and i......

The peptide mimicking small extracellular ring domain of CD82 inhibits tumor cell migration in vitro and metastasis in vivo (Apr, 10.1007/s00432-021-03595-6, 2021)

期刊: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021; 147 (7)

A correction to this paper has been published: http://fcb4e4bc18db4e2ead7856820ff3646c.ebe14e7a.libvpn.zuel.edu.cn/10.1007/s00432-021-03649-9

Relationship between lung function and lung cancer risk: a pooled analysis of cohorts plus Mendelian randomization study

期刊: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021; 147 (10)

Background Since little consensus has been reached on whether milder reduction in forced expiratory volume in 1 s (FEV1) increases lung cancer inciden......

Targeting tumor vascularization: promising strategies for vascular normalization

期刊: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021; 147 (9)

Tumor recurrence after the clinical cure of tumor often results from the presence of an abnormal microenvironment, including an aberrant vasculature. ......

The peptide mimicking small extracellular ring domain of CD82 inhibits tumor cell migration in vitro and metastasis in vivo

期刊: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021; 147 (7)

Background Tetraspanin KAI1/CD82, a tumor metastasis suppressor, has emerged as a promising molecular target for the management of metastatic disease.......

Human umbilical cord mesenchymal stem cells-derived exosomal microRNA-181a retards nasopharyngeal carcinoma development by mediating KDM5C

期刊: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021; 147 (10)

Objective It has been studied that mesenchymal stem cells (MSCs)-derived exosomes could suppress tumor growth in nasopharyngeal carcinoma (NPC) and mi......

NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers

期刊: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021; 147 (7)

Purpose Downregulation of MHC class I (MHC-I) is a common immune evasion strategy of many cancers. Similarly, two allogeneic clonal transmissible canc......

The status of WIF1 methylation in cell-free DNA is associated with the insusceptibility for gefitinib in the treatment of lung cancer

期刊: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021; 147 (8)

Background Targeted cancer therapy has shed light on the treatment of tumor, especially for patients with non-small cell lung cancer. However, only a ......

The log odds of negative lymph nodes/T stage: a new prognostic and predictive tool for resected gastric cancer patients

期刊: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021; 147 (8)

Purpose When only the TNM classification is used to predict survival in gastric cancer (GC) patients, the impact of the degree of lymphadenectomy on t......

Apatinib combined with PD-L1 blockade synergistically enhances antitumor immune responses and promotes HEV formation in gastric cancer

期刊: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021; 147 (8)

Purpose Apatinib, an antiangiogenic drug, has shown beneficial effects only in a fraction of advanced gastric cancer (GC) patients. Given the recent s......

A review: hippo signaling pathway promotes tumor invasion and metastasis by regulating target gene expression

期刊: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2021; 147 (6)

Background The Hippo pathway is widely considered to inhibit cell growth and play an important role in regulating the size of organs. However, recent ......

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