期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (4)
Small cell lung cancer (SCLC) is characterized by a high relapse rate, drug tolerance, and limited treatment choices. Chimeric antigen receptor (CAR)-......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (3)
Clearance of airway intruders by immune cells is required to resolve infectious pneumonia. However, the molecular mechanisms underlying this process r......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (4)
IL-10-producing regulatory B (Breg) cells are well recognized for maintaining immune tolerance. The impaired Breg cell function with decreased IL-10-p......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 111 (5)
Mesenchymal stem cell transplantation (MSCT) regulates immune cells, and is a promising therapeutic approach for treating autoimmune diseases. Stem ce......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (2)
Paroxysmal nocturnal hemoglobinuria (PNH) is a disease involving hematopoietic stem cell membrane defects caused by acquired phosphatidylinositol glyc......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (4)
Acute myeloid leukemia (AML) is a hematologic malignant disease largely affecting older adults with poor outcomes. Lack of effective targeted treatmen......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (6)
Diffuse large B-cell lymphoma (DLBCL) is the most common invasive type of non-Hodgkin lymphoma. Cell-of-origin (COO) classification is related to pati......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 111 (3)
Diabetic nephropathy (DN) is a leading cause of end-stage renal failure. The study aimed to investigate whether long noncoding RNA taurine-upregulated......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 111 (4)
Hemin, a substrate of heme oxygenase (HO)-1, induces HO-1 expression on a variety of cells to exert anti-oxidant and anti-inflammatory roles. However,......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (3)
Influenza viruses continue to threaten public health, and currently available vaccines provide insufficient immunity against seasonal and pandemic inf......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (1)
K48-linked ubiquitination determines antigen degradation and plays vital roles in the process of cross-presentation of bone marrow precursor cell (BMP......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (3)
With the concept of the gut-lung axis reinforced in recent years, emerging evidence has shown that intestinal homeostasis is vital for lung health. Ne......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (4)
T-cell malignancies, including T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoma (TCL), are characterized by inferior treatment effects,......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (5)
Primary biliary cholangitis (PBC) is characterized as interlobular bile duct injury and fibrosis, which results from the loss of tolerance to self-ant......
期刊: JOURNAL OF LEUKOCYTE BIOLOGY, 2022; 112 (6)
T lymphocytes are the key protective contributors in chronic infection and tumor, but experience exhaustion by persistent antigen stimulation. As an u......