期刊： CHEMICO-BIOLOGICAL INTERACTIONS, 2023; 369 ()
Compounds with 3,4-fused tricyclic indole (FTI) frameworks are attractive scaffolds for drug discovery. We synthesized FTI-6D, a compound with this fr......
期刊： CHEMICO-BIOLOGICAL INTERACTIONS, 2023; 382 ()
Ketorolac tromethamine (KT), is a widely used non-steroidal anti-inflammatory drug (NSAID) for treating moderate to severe pain. However, the use of K......
期刊： CHEMICO-BIOLOGICAL INTERACTIONS, 2023; 386 ()
Alzheimer's disease (AD) pathogenesis has been attributed to extracellular aggregates of amyloid beta (A beta) plaques and neurofibrillary tangles in ......
期刊： CHEMICO-BIOLOGICAL INTERACTIONS, 2023; 375 ()
Hyperinsulinemia (HI) induced insulin resistance (IR) and associated pathologies are the burning and unsolvable issues in diabetes treatment. The cell......
期刊： CHEMICO-BIOLOGICAL INTERACTIONS, 2023; 378 ()
Diabetic kidney disease (DKD), as a chronic diabetes-induced complication, is considered the most frequent leading cause of end-stage renal disease (E......
期刊： CHEMICO-BIOLOGICAL INTERACTIONS, 2023; 382 ()
Cytochrome c, an iron containing metalloprotein in the mitochondria of the cells with an oxide/redox property, plays key role in the cell apoptotic pa......
期刊： CHEMICO-BIOLOGICAL INTERACTIONS, 2023; 385 ()
Myocardial infarction (MI) is a life-threatening ischemic disease and is one of the leading causes of morbidity and mortality worldwide. Punicalagin (......
期刊： CHEMICO-BIOLOGICAL INTERACTIONS, 2023; 373 ()
Trans-Caryophyllene (TC), a sesquiterpene, with proven biological activities, which in this work was tested alone, encapsulated in liposomes and assoc......
期刊： CHEMICO-BIOLOGICAL INTERACTIONS, 2023; 374 ()
Liver damage has been induced in animal experiments using carbon tetrachloride (CCl4), a potent hepatotoxin. CCl4 is activated by cytochrome P450 2E1,......
期刊： CHEMICO-BIOLOGICAL INTERACTIONS, 2023; 374 ()
Arsenic is widely available in the environment and arsenic toxicity is a public health problem of serious concern worldwide. Zingerone is a promising ......
期刊： CHEMICO-BIOLOGICAL INTERACTIONS, 2023; 376 ()
While oocytes and embryos cryopreservation can favor some patients with cancer-induced infertility to achieve pregnancy, the development of effective ......
期刊： CHEMICO-BIOLOGICAL INTERACTIONS, 2023; 382 ()
This study shows the EDTA-resistant, Ca2+ and Cu2+-dependent hydrolysis of O-hexyl 2,5-dichlorophenyl phosphoramidate (HDCP) compound in reptiles sera......
期刊： CHEMICO-BIOLOGICAL INTERACTIONS, 2023; 383 ()
Butyrylcholinesterase (BChE), an enzyme primarily found in the liver, plasma, and brain, has been recognized for its role in the hydrolysis of choline......
期刊： CHEMICO-BIOLOGICAL INTERACTIONS, 2023; 384 ()
The crystal structure of the Thermoanaerobacterium xylanolyticum in glycoside hydrolase family 116 (TxGH116) beta-glucosidase provides a structural mo......
