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Pallidal stimulation as treatment for camptocormia in Parkinson's disease (vol 7, 8, 2021)

期刊: NPJ PARKINSONS DISEASE, 2021; 7 (1)

A Correction to this paper has been published: http://fcb4e4bc18db4e2ead7856820ff3646c.ebe14e7a.libvpn.zuel.edu.cn/10.1038/s41531-021-00178-7

A transcriptome-wide association study identifies susceptibility genes for Parkinson's disease

期刊: NPJ PARKINSONS DISEASE, 2021; 7 (1)

Genome-wide association study (GWAS) has seen great strides in revealing initial insights into the genetic architecture of Parkinson's disease (PD). S......

Longitudinal evolution of non-motor symptoms in early Parkinson's disease: a 3-year prospective cohort study

期刊: NPJ PARKINSONS DISEASE, 2021; 7 (1)

The progression of global non-motor symptoms (NMS) in Chinese patients with Parkinson's disease (PD) has not been explored. We aimed to examine the lo......

Balance response to levodopa predicts balance improvement after bilateral subthalamic nucleus deep brain stimulation in Parkinson's disease

期刊: NPJ PARKINSONS DISEASE, 2021; 7 (1)

The effect of subthalamic nucleus deep brain stimulation (STN-DBS) on balance function in patients with Parkinson's disease (PD) and the potential out......

Lateralized effects of deep brain stimulation in Parkinson's disease: evidence and controversies

期刊: NPJ PARKINSONS DISEASE, 2021; 7 (1)

The bilateral effects of deep brain stimulation (DBS) on motor and non-motor symptoms of Parkinson's disease (PD) have been extensively studied and re......

Corneal nerve fiber loss relates to cognitive impairment in patients with Parkinson's disease

期刊: NPJ PARKINSONS DISEASE, 2021; 7 (1)

Cognitive impairment in Parkinson's disease (PD) adversely influences quality of life. There is currently no available biomarker to predict cognitive ......

Genetic and environmental factors in Alzheimer's and Parkinson's diseases and promising therapeutic intervention via fecal microbiota transplantation

期刊: NPJ PARKINSONS DISEASE, 2021; 7 (1)

Neurodegenerative diseases are characterized by neuronal impairment and loss of function, and with the major shared histopathological hallmarks of mis......

Abnormal interhemispheric resting state functional connectivity in Parkinson's disease patients with impulse control disorders

期刊: NPJ PARKINSONS DISEASE, 2021; 7 (1)

Impulse control disorders (ICD) in Parkinson's disease (PD) might be attributed to misestimate of rewards or the failure to curb inappropriate choices......

"Hot cross bun" is a potential imaging marker for the severity of cerebellar ataxia in MSA-C

期刊: NPJ PARKINSONS DISEASE, 2021; 7 (1)

To evaluate the correlation between "hot cross bun" sign (HCBs) and disease severity in multiple system atrophy (MSA). We recruited patients with prob......

Rheumatoid arthritis decreases risk for Parkinson's disease: a Mendelian randomization study

期刊: NPJ PARKINSONS DISEASE, 2021; 7 (1)

Epidemiological and clinical studies have suggested comorbidity between rheumatoid arthritis and Parkinson's disease (PD), but whether there exists a ......

The role of brain perivascular space burden in early-stage Parkinson's disease

期刊: NPJ PARKINSONS DISEASE, 2021; 7 (1)

Perivascular space (PVS) is associated with neurodegenerative diseases, while its effect on Parkinson's disease (PD) remains unclear. We aimed to inve......

Pallidal stimulation as treatment for camptocormia in Parkinson's disease

期刊: NPJ PARKINSONS DISEASE, 2021; 7 (1)

Camptocormia is a common and often debilitating postural deformity in Parkinson's disease (PD). Few treatments are currently effective. Deep brain sti......

Altered interhemispheric synchrony in Parkinson's disease patients with levodopa-induced dyskinesias

期刊: NPJ PARKINSONS DISEASE, 2020; 6 (1)

Levodopa-induced dyskinesias are common motor complication of Parkinson's disease after 4-6 years of treatment. The hallmarks of dyskinesias include u......

Repetitive transcranial magnetic stimulation improves Parkinson's freezing of gait via normalizing brain connectivity

期刊: NPJ PARKINSONS DISEASE, 2020; 6 (1)

Robust, effective treatments for Parkinson's freezing of gait remain elusive. Our previous study revealed beneficial effects of high-frequency rTMS ov......

Multiple comorbid sleep disorders adversely affect quality of life in Parkinson's disease patients

期刊: NPJ PARKINSONS DISEASE, 2020; 6 (1)

Sleep disorders are common non-motor symptoms in patients with Parkinson's disease (PD). The characteristics and impact of multiple comorbid sleep dis......

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