期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ()
Hexokinase (HK) catalyzes the first step in glucose metabolism, making it an exciting target for the inhibition of tumor initiation and progression du......
期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 297 (2)
Apart from prevention using vaccinations, the management options for COVID-19 remain limited. In retrospective cohort studies, use of famotidine, a sp......
期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ()
Diseases of the glomerular basement membrane (GBM), such as Goodpasture's disease (GP) and Alport syndrome (AS), are a major cause of chronic kidney f......
期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ()
Vascular smooth muscle cells (VSMCs) contribute to the deposition of extracellular matrix proteins (ECMs), including Type IV collagen, in the vessel w......
期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 297 (2)
The p75 neurotrophin receptor (p75(NTR)) is a critical mediator of neuronal death and tissue remodeling and has been implicated in various neurodegene......
期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ()
When plants are exposed to high-light conditions, the potentially harmful excess energy is dissipated as heat, a process called non-photochemical quen......
期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ()
The carnitine/organic cation transporter novel 2 (OCTN2) is responsible for the cellular uptake of carnitine in most tissues. Being a transmembrane pr......
期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ()
Obesity associates with inflammation, insulin resistance, and higher blood lipids. It is unclear if immune responses facilitate lipid breakdown and re......
期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ()
Prion diseases are a group of neurodegenerative disorders that infect animals and humans with proteinaceous particles called prions. Prions consist of......
期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ()
RNA polymerase II (Pol II) surveils the genome, pausing as it encounters DNA lesions and base modifications and initiating signals for DNA repair amon......
期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ()
Proper repair of damaged DNA is critical for the maintenance of genome stability. A complex composed of Integrator subunit 3 (Ints3), single-stranded ......
期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ()
Chronic endoplasmic reticulum stress resulting from mis-folding of the visual pigment rhodopsin (RHO) can lead to loss of rod photoreceptors, which in......
期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ()
Unchecked inflammation can result in severe diseases with high mortality, such as macrophage activation syndrome (MAS). MAS and associated cytokine st......
期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ()
Proper expression of Homeobox A cluster genes (HoxA) is essential for embryonic stem cell (ESC) differentiation and individual development. However, m......
期刊： JOURNAL OF BIOLOGICAL CHEMISTRY, 2021; 296 ()
Sterol homeostasis is tightly controlled by molecules that are highly conserved from yeast to humans, the dysregulation of which plays critical roles ......
