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Plasma DNA Integrity as a Prognostic Biomarker for Colorectal Cancer Chemotherapy

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

Objectives. To verify whether the concentrations and integrity index of circulating cell-free DNA (cfDNA) in serum may be clinically useful for the pr......

Systematic Pan-Cancer Population-Based Analysis Reveals the Incidence and Prognosis of Lung Metastases at Diagnosis

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

Background. Metastasis is one of the most prevalent causes of death in cancer patients and the lungs are among the organs most commonly affected by me......

Safety Analysis of Apatinib Combined with Chemotherapy in the Treatment of Advanced Gastric Carcinoma: A Randomised Controlled Trial

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

Objective. To study the safety of apatinib combined with chemotherapy in the treatment of advanced gastric carcinoma (GCA). Methods. 74 patients with ......

Activity and Safety of Tegafur, Gimeracil, and Oteracil Potassium for Nasopharyngeal Carcinoma: A Systematic Review and Meta-Analysis

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

In clinical practice, tegafur, gimeracil, and oteracil potassium (S-1) therapy is commonly administered to treat nasopharyngeal carcinoma (NPC). Howev......

Id4 Suppresses the Growth and Invasion of Colorectal Cancer HCT116 Cells through CK18-Related Inhibition of AKT and EMT Signaling

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

Id4 is one of the inhibitors of DNA-binding proteins (Id) and involved in the pathogenesis of numerous cancers. The specific mechanism underlying the ......

Prognostic Variables of Younger-Aged Cervical Carcinoma Patients: A Retrospective Study

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

Purpose. The prevalence of carcinoma of the cervix is increasing in younger women. This study aimed to evaluate the sociodemographic, pathological, an......

Prognostic Value of Albumin to D-Dimer Ratio in Advanced Gastric Cancer

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

Gastric cancer (GC) is one of the most common malignancies worldwide. Notably, patients with advanced GC have a poor prognosis and quality of life, pr......

A Comprehensive Pan-Cancer Analysis of RBM8A Based on Data Mining

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

Background. As a member of the exon junction complex (EJC), RNA-binding motif protein 8A (RBM8A) plays a crucial role in the maintenance of mRNA and m......

All-Trans Retinoic Acid Enhances Chemosensitivity to 5-FU by Targeting miR-378c/E2F7 Axis in Colorectal Cancer

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

Colorectal carcinoma (CRC), a life-threatening malignancy, has been found to present resistance to 5-fluorouracil (5-FU) and cause a poor prognosis fo......

Effect of Gambogic Acid on miR-199a-3p Expression and Cell Biological Behavior in Colorectal Cancer Cells

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

Colorectal cancer (CC), as a malignancy threatening life and health, has a rising incidence in recent years. It has been reported that gambogic acid (......

Involvement of TRPC7-AS1 Expression in Hepatitis B Virus-Related Hepatocellular Carcinoma

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

Objective. To investigate the expression of transient receptor potential (TRP) superfamily genes, especially TRPC7-AS1 in hepatitis B virus- (HBV-) re......

LncRNA NKILA Promotes Epithelial-Mesenchymal Transition of Liver Cancer Cells by Targeting miR-485-5p

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

Objective. Liver cancer (LC), one of the familiar malignancies, has a very high morbidity all over the world. The onset of the disease is hidden, and ......

Chemerin-9 Attenuates Experimental Abdominal Aortic Aneurysm Formation in ApoE(-/-) Mice

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

Chronic inflammation plays an essential role in the pathogenesis of abdominal aortic aneurysm (AAA), a progressive segmental abdominal aortic dilation......

miR-1224-3p Promotes Breast Cancer Cell Proliferation and Migration through PGM5-Mediated Aerobic Glycolysis

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

Metabolic reprogramming of aerobic glycolysis is a hallmark of cancer cells. Regulators of aerobic glycolysis have become targets for cancer diagnosis......

Discovery and Validation of Circulating EVL mRNA as a Prognostic Biomarker in Pancreatic Cancer

期刊: JOURNAL OF ONCOLOGY, 2021; 2021 ()

Background. Circulating plasma mRNAs can be analyzed to identify putative cancer biomarkers. This study was conducted in an effort to detect plasma mR......

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