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Blockade of metabotropic glutamate receptor 5 attenuates axonal degeneration in 6-hydroxydopamine-induced model of Parkinson's disease

期刊: MOLECULAR AND CELLULAR NEUROSCIENCE, 2021; 110 ()

Although there are numerous strategies to counteract the death of dopaminergic neurons in Parkinson's disease (PD), there are currently no treatments ......

Identification of novel A beta-LilrB2 inhibitors as potential therapeutic agents for Alzheimer's disease

期刊: MOLECULAR AND CELLULAR NEUROSCIENCE, 2021; 114 ()

LilrB2 is an A beta receptor with high affinity, which not only contributes to memory deficits but also mediates the loss of synaptic plasticity. Thus......

Hepcidin inhibits autophagy in intracerebral hemorrhage models in vitro and in vivo

期刊: MOLECULAR AND CELLULAR NEUROSCIENCE, 2021; 111 ()

Iron has a key role in the activation of the autophagic pathway in rats with intracerebral hemorrhage (ICH), and hepcidin has the ability to reduce br......

CHRNA1 promotes the pathogenesis of primary focal hyperhidrosis

期刊: MOLECULAR AND CELLULAR NEUROSCIENCE, 2021; 111 ()

The aim of the study was to elucidate the involvement of cholinergic receptor nicotinic alpha 1 subunit (CHRNA1) in the pathogenesis of primary focal ......

Matrix metalloprotease-mediated cleavage of neural glial-related cell adhesion molecules activates quiescent olfactory stem cells via EGFR

期刊: MOLECULAR AND CELLULAR NEUROSCIENCE, 2020; 108 ()

Quiescent stem cells have been found in multiple adult organs, and activation of these stem cells is critical to the restoration of damaged tissues in......

Effects of RU486 treatment after single prolonged stress depend on the post-stress interval

期刊: MOLECULAR AND CELLULAR NEUROSCIENCE, 2020; 108 ()

The Single Prolonged Stress protocol is considered a model for PTSD, as it induces long lasting changes in rat behaviour and endocrine regulation. Pre......

L-type Ca2+ channels and charybdotoxin-sensitive Ca2+-activated K+ channels are required for reduction of GABAergic activity induced by beta 2-adrenoceptor in the prefrontal cortex

期刊: MOLECULAR AND CELLULAR NEUROSCIENCE, 2019; 101 ()

Whereas beta 2-adrenoceptor (beta 2-AR) has been reported to reduce GABAergic activity in the prefrontal cortex (PFC), the underlying cellular and mol......

JIF:2.86

PLD1 promotes dendritic spine morphogenesis via activating PKD1

期刊: MOLECULAR AND CELLULAR NEUROSCIENCE, 2019; 99 ()

Dendritic spines on the dendrites of pyramidal neurons are one of the most important components for excitatory synapses, where excitatory information ......

JIF:2.86

A disintegrin and metalloproteinase with thrombospondin motifs 2 cleaves and inactivates Reelin in the postnatal cerebral cortex and hippocampus, but not in the cerebellum

期刊: MOLECULAR AND CELLULAR NEUROSCIENCE, 2019; 100 ()

Reelin plays important roles in regulating neuronal development, modulating synaptic function, and counter-acting amyloid beta toxicity. A specific pr......

JIF:2.86

TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration

期刊: MOLECULAR AND CELLULAR NEUROSCIENCE, 2019; 100 ()

Genetic mutations in TAR DNA-binding protein 43 (TDP-43) cause amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Importantly, TDP......

JIF:2.86

Heat shock protein 70 suppresses neuroinflammation induced by alpha-synuclein in astrocytes

期刊: MOLECULAR AND CELLULAR NEUROSCIENCE, 2018; 86 ()

Neuroinflammation triggered by activation of glial cells plays an important role in the pathophysiology of several neurodegenerative diseases includin......

JIF:2.86

Exosome-associated tau exacerbates brain functional impairments induced by traumatic brain injury in mice

期刊: MOLECULAR AND CELLULAR NEUROSCIENCE, 2018; 88 ()

Traumatic brain injury (TBI) has been associated with an increased risk for neurodegenerative diseases, and Tau spread and accumulation might be one o......

JIF:2.86

Reproductive role of miRNA in the hypothalamic-pituitary axis

期刊: MOLECULAR AND CELLULAR NEUROSCIENCE, 2018; 88 ()

The hypothalamic-pituitary-gonz dal (HPG) axis plays a critical role in regulating reproductive function. Gonadotropin-releasing hormone (GnRH), which......

JIF:2.86

Deletion of Kir6.2/SUR1 potassium channels rescues diminishing of DA neurons via decreasing iron accumulation in PD

期刊: MOLECULAR AND CELLULAR NEUROSCIENCE, 2018; 92 ()

ATP-sensitive potassium (K-ATP) channels express in the central nervous system extensively which coupling cell metabolism and cellular electrical acti......

JIF:2.86

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