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The Time Course of Facial Expression Recognition Using Spatial Frequency Information: Comparing Pain and Core Emotions

期刊: JOURNAL OF PAIN, 2021; 22 (2)

We are able to recognize others' experience of pain from their facial expressions. However, little is known about what makes the recognition of pain p......

P2X4R Contributes to Central Disinhibition Via TNF-alpha/TNFR1/GABAaR Pathway in Post-stroke Pain Rats

期刊: JOURNAL OF PAIN, 2021; 22 (8)

Central post-stroke pain (CPSP) is a disabling condition in stroke patients. It is a type of neuropathic pain for which the mechanism and relevant dru......

Non-Surgical Interventions for Lumbar Spinal Stenosis Leading To Neurogenic Claudication: A Clinical Practice Guideline

期刊: JOURNAL OF PAIN, 2021; 22 (9)

Lumbar spinal stenosis (LSS) causing neurogenic claudication (NC) is increasingly common with an aging population and can be associated with significa......

Gender Biases in Estimation of Others' Pain

期刊: JOURNAL OF PAIN, 2021; 22 (9)

Caregiving and other interpersonal interactions often require accurate perception of others' pain from nonverbal cues, but perceivers may be subject t......

Injectable PLGA-Coated Ropivacaine Produces A Long-Lasting Analgesic Effect on Incisional Pain and Neuropathic Pain

期刊: JOURNAL OF PAIN, 2021; 22 (2)

The management of persistent postsurgical pain and neuropathic pain remains a challenge in the clinic. Local anesthetics have been widely used as simp......

Prospective Associations of Frequent Pain Symptoms With Suicidal Behavior in Adolescents

期刊: JOURNAL OF PAIN, 2021; 22 (7)

Chronic pain and suicidal behavior are prevalent in adolescents. This longitudinal study examined the associations between pain symptoms and suicidal ......

Median Nerve Stimulation as a Nonpharmacological Approach to Bypass Analgesic Tolerance to Morphine: A Proof-of-Concept Study in Mice

期刊: JOURNAL OF PAIN, 2021; 22 (3)

Analgesic tolerance to opioids contributes to the opioid crisis by increasing the quantity of opioids prescribed and consumed. Thus, there is a need t......

Calcium Channel alpha 2 delta 1 Subunit Mediates Secondary Orofacial Hyperalgesia Through PKC-TRPA1/Gap Junction Signaling

期刊: JOURNAL OF PAIN, 2020; 21 (1-2)

Orofacial pain is characterized by its easy spread to adjacent areas, thus presenting with primary hyperalgesia (hypersensitivity at the site of injur......

Spinal DN-9, a Peptidic Multifunctional Opioid/Neuropeptide FF Agonist Produced Potent Nontolerance Forming Analgesia With Limited Side Effects

期刊: JOURNAL OF PAIN, 2020; 21 (3-4)

The development of multitarget opioid drugs has emerged as an attractive therapeutic strategy to eliminate opioid-related side effects. Our previous s......

Altered Spontaneous Activity and Functional Connectivity in the Posterior Pons of Patients With Migraine Without Aura

期刊: JOURNAL OF PAIN, 2020; 21 (3-4)

The brainstem has been discussed as the main player in the pathogenesis of migraine. Dysfunctional brainstem nuclei and their abnormal connections to ......

Determining Real Change in Conditioned Pain Modulation: A Repeated Measures Study in Healthy Volunteers

期刊: JOURNAL OF PAIN, 2020; 21 (5-6)

Conditioned pain modulation (CPM) is a potentially useful biomarker in pain populations; however, a statistically robust interpretation of change scor......

Shared Sensitivity to Physical Pain and Social Evaluation

期刊: JOURNAL OF PAIN, 2020; 21 (5-6)

Many studies have demonstrated a link between experiences of physical pain and those of social rejection, both of which can trigger cognitive processe......

Evaluating the Effects of Acupuncture Using a Dental Pain Model in Healthy Subjects - A Randomized, Cross-Over Trial

期刊: JOURNAL OF PAIN, 2020; 21 (3-4)

Acupuncture is a complementary and nonpharmacological intervention that can be effective for the management of chronic pain in addition to or instead ......

Alternative Splicing of Nrcam Gene in Dorsal Root Ganglion Contributes to Neuropathic Pain

期刊: JOURNAL OF PAIN, 2020; 21 (7-8)

NrCAM, a neuronal cell adhesion molecule in the L1 family of the immunoglobulin superfamily, is subjected to extensively alternative splicing and invo......

IFN beta Treatment Inhibits Nerve Injury-induced Mechanical Allodynia and MAPK Signaling By Activating ISG15 in Mouse Spinal Cord

期刊: JOURNAL OF PAIN, 2020; 21 (7-8)

Neuropathic pain is difficult to treat and remains a major clinical challenge worldwide. While the mechanisms which underlie the development of neurop......

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