期刊: CANCER LETTERS, 2023; 562 ()
Glioblastoma (GB) is a malignant and immune-suppressed brain cancer that remains incurable despite the current standard of care. Radiotherapy is a mai......
期刊: CANCER LETTERS, 2023; 562 ()
Obesity has been linked to a higher risk of pancreatic cancer. However, the mechanism by which obesity promote pancreatic carcinogenesis is still uncl......
期刊: CANCER LETTERS, 2023; 568 ()
Pancreatic ductal adenocarcinoma (PDAC) is characterized by hypoxic tumor microenvironment (TME), which aids tumor progression, drug resistance, and i......
期刊: CANCER LETTERS, 2023; 574 ()
Pleural mesothelioma (PM) is characterized by poor prognosis and limited therapeutic options. Y-box-binding protein 1 (YB-1) was shown to drive growth......
期刊: CANCER LETTERS, 2023; 559 ()
The fibrinolytic system is involved in many physiological functions, among which the important members can interact with each other, either synergisti......
期刊: CANCER LETTERS, 2023; 562 ()
IFN gamma signaling is mainly mediated through the activation of the canonical JAK-STAT signaling pathway, tran-scription factors, and epigenetic modi......
期刊: CANCER LETTERS, 2023; 566 ()
HCC remains one of the most prevalent and deadliest cancers. Serum AFP level is a biomarker for clinical diagnosis of HCC, instead the contribution of......
期刊: CANCER LETTERS, 2023; 566 ()
Castration-resistant prostate cancer (CRPC) responds poorly to existing therapy and appears as the lethal consequence of prostate cancer (PCa) progres......
期刊: CANCER LETTERS, 2023; 564 ()
Metastatic Renal Cell Carcinoma (mRCC) remains incurable, despite the current checkpoint-blockade-driven, limited overall response rate. The CD8+ memo......
期刊: CANCER LETTERS, 2023; 565 ()
Small-molecule EGFR inhibitors have distinctly improved the overall survival especially in EGFR-mutated lung cancer. However, their use is often limit......
期刊: CANCER LETTERS, 2023; 566 ()
O-linked & beta;-D-N-acetylglucosamine (O-GlcNAc), as a posttranslational modification (PTM), is a reversible reaction that attaches & beta;-N......
期刊: CANCER LETTERS, 2023; 567 ()
Effector, memory and exhaustion are three phenotypes of CD8+ T cell. In tumor microenvironment (TME), metabolism dysfunction of the three should take ......
期刊: CANCER LETTERS, 2023; 570 ()
Cancer poses a significant global health burden, necessitating the widespread use of chemotherapy and radiotherapy as conventional frontline intervent......
期刊: CANCER LETTERS, 2023; 576 ()
LIM kinase 1 (LIMK1) is a member of the LIMK family that has been considered to be involved in chemoresistance in various tumors, and N6-methyladenosi......