期刊： NATURE REVIEWS CLINICAL ONCOLOGY, 2021; 18 (9)
Many tumour antigens that do not arise from cancer cell-specific mutations are targets of humoral and cellular immunity despite their expression on no......
期刊： NATURE REVIEWS CLINICAL ONCOLOGY, ; ()
The immune system has crucial roles in cancer development and treatment. Whereas adaptive immunity can prevent or constrain cancer through immunosurve......
期刊： NATURE REVIEWS CLINICAL ONCOLOGY, ; ()
Ferroptosis is an iron-dependent form of regulated cell death driven by excessive lipid peroxidation. Pharmacological agents, ionizing radiation and c......
期刊： NATURE REVIEWS CLINICAL ONCOLOGY, ; ()
Patients with cancer have a high risk of morbidity and mortality from COVID-19. The rapid development of COVID-19 vaccines has provided new hope of mi......
期刊： NATURE REVIEWS CLINICAL ONCOLOGY, 2020; 17 (1)
Local administration of oncolytic viruses to tumours can promote anticancer immune responses that lead to the abscopal regression of distant metastase......
期刊： NATURE REVIEWS CLINICAL ONCOLOGY, 2020; 17 (9)
Cell-free DNA and proteins are secreted into the bloodstream by multiple types of cancer. In a recently published prospective study involving 10,006 w......
期刊： NATURE REVIEWS CLINICAL ONCOLOGY, 2020; 17 (10)
Zanubrutinib was recently granted expedited approval by the USA and Chinese drug regulatory authorities for the treatment of mantle cell lymphoma, thu......
期刊： NATURE REVIEWS CLINICAL ONCOLOGY, 2020; 17 (11)
Light-activated, photosensitizer-based therapies have been established as safe modalities of tumour ablation for numerous cancer indications. Two main......
期刊： NATURE REVIEWS CLINICAL ONCOLOGY, 2020; 17 (11)
Measuring the methylation status of cell-free DNA (cfDNA) in plasma holds great potential for the early, noninvasive detection of cancer. Two recent p......
期刊： NATURE REVIEWS CLINICAL ONCOLOGY, 2020; 17 (12)
The efficacy of chemotherapy in patients with cancer is now known to have an immunogenic component. Nonetheless, chemotherapy alone often fails to pro......
期刊： NATURE REVIEWS CLINICAL ONCOLOGY, 2019; 16 (10)
Diffuse large B cell lymphoma (DLBCL) is a highly heterogeneous lymphoid neoplasm with variations in gene expression profiles and genetic alterations,......
期刊： NATURE REVIEWS CLINICAL ONCOLOGY, 2019; 16 (5)
In the past decade, the development of a genome-editing technology mediated by CRISPR has made genetic engineering easier than ever, both in vitro and......
期刊： NATURE REVIEWS CLINICAL ONCOLOGY, 2019; 16 (9)
Targeted therapy and immunotherapy have greatly improved the prognosis of patients with metastatic melanoma, but resistance to these therapeutic modal......
期刊： NATURE REVIEWS CLINICAL ONCOLOGY, 2022; 19 (5)
Antibodies targeting PD-1 or its ligand PD-L1 have revolutionized cancer therapy. Increased understanding of the mechanisms regulating PD-L1 has revea......
