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Identification of potential biomarkers in dengue via integrated bioinformatic analysis

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (8)

Dengue fever virus (DENV) is a global health threat that is becoming increasingly critical. However, the pathogenesis of dengue has not yet been fully......

Misdiagnosis of scrub typhus as hemorrhagic fever with renal syndrome and potential co-infection of both diseases in patients in Shandong Province, China, 2013-2014

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (3)

Background Scrub typhus, caused by Orientia tsutsugamushi, an obligate intracellular gram-negative bacterium, along with hemorrhagic fever with renal ......

Impact of deltamethrin-resistance in Aedes albopictus on its fitness cost and vector competence

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (4)

BackgroundAedes albopictus is one of the most invasive species in the world as well as the important vector for mosquito-borne diseases such as dengue......

DNA vaccination induced protective immunity against SARS CoV-2 infection in hamsterss

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (5)

The development of efficient vaccines against COVID-19 is an emergent need for global public health. The spike protein of severe acute respiratory syn......

Recombinant cystatin-like protein-based competition ELISA for Trichinella spiralis antibody test in multihost sera

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (8)

Objectives Trichinella spiralis is a zoonotic parasite with a complex parasitic life cycle and exposed to animals or humans by infectious meat. To con......

Trichomonas vaginalis infection impairs anion secretion in vaginal epithelium

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (4)

Author summary Trichomonas vaginalis is a common sexually transmitted parasite that colonized the urogenital mucosa and causes trichomoniasis, a negle......

An inactivated recombinant rabies virus displaying the Zika virus prM-E induces protective immunity against both pathogens

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (6)

The global spread of Zika virus (ZIKV), which caused a pandemic associated with Congenital Zika Syndrome and neuropathology in newborns and adults, pr......

Genomic and epidemiological characteristics of SARS-CoV-2 in Africa

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (4)

Since late 2019, the coronavirus disease 2019 (COVID-19) outbreak, caused by SARS-CoV-2, has rapidly evolved to become a global pandemic. Each country......

Aedes aegypti SNAP and a calcium transporter ATPase influence dengue virus dissemination

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (6)

Dengue virus (DENV) is a flavivirus that causes marked human morbidity and mortality worldwide, and is transmitted to humans by Aedes aegypti mosquito......

Elimination of schistosomiasis in China: Current status and future prospects

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (8)

Elimination of schistosomiasis as a public health problem among all disease-endemic countries in 2030 is an ambitious goal. Recent achievements result......

Meta-analysis of the prevalence of Echinococcus in dogs in China from 2010 to 2019

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (4)

Background Echinococcosis (canine Echinococcus disease) is a neglected tropical disease that causes serious public harm. Dogs, as a terminal host of E......

Geographical Detector-based influence factors analysis for Echinococcosis prevalence in Tibet, China

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (7)

Author summary Echinococcosis, a worldwide zoonosis caused by genus Echinococcus, is highly endemic in Tibet of China. CE and AE as two main types of ......

Findings from the initial Stepwise Approach to Rabies Elimination (SARE) Assessment in China, 2019

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (3)

In 2015, China and other member states of the United Nations adopted the goal of eliminating dog-mediated rabies by 2030. China has made substantial p......

Predicting the environmental suitability for onchocerciasis in Africa as an aid to elimination planning

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (7)

Author summary As of 2018, it was unknown if onchocerciasis transmission occurred among approximately 2 400 implementation units (IUs; typically, seco......

Spatiotemporal distribution and sociodemographic and socioeconomic factors associated with primary and secondary syphilis in Guangdong, China, 2005-2017

期刊: PLOS NEGLECTED TROPICAL DISEASES, 2021; 15 (8)

Background Previous studies exploring the factors associated with the incidence of syphilis have mostly focused on individual-level factors. However, ......

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