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Bis(ethylmaltolato)oxidovanadium (IV) alleviates neuronal apoptosis through regulating peroxisome proliferator-activated receptor gamma in a triple transgenic animal model of Alzheimer's disease

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2021; 26 (5)

Endoplasmic reticulum stress (ER stress) plays a critical role in neuronal apoptosis along with the aggravation of Alzheimer's disease (AD). Nuclear r......

Design and synthesis of N-hydroxyalkyl substituted deferiprone: a kind of iron chelating agents for Parkinson's disease chelation therapy strategy

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2021; 26 (4)

The blood-brain barrier (BBB) permeability of molecules needs to meet stringent requirements of Lipinski's rule, which pose a difficulty for the ratio......

Two biologically inspired tetranuclear nickel(II) catalysts: effect of the geometry of Ni-4 core on electrocatalytic water oxidation

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, ; ()

Two biologically inspired tetranuclear nickel complexes [Ni-4(L-H)(4)(CH3COO)(3)]center dot Cl (1) and [Ni-4(L-H)(4)(CH3COO)(4)]center dot 2CH(3)OH (2......

A novel quinoline-based turn-on fluorescent probe for the highly selective detection of Al (III) and its bioimaging in living cells, plants tissues and zebrafish

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2021; 26 (1)

A novel quinoline fluorescent probe QNP ((E)-N '-(5-chloro-2-hydroxybenzylidene) quinoline-2-carbohydrazide) for detection of Al3+ ion was designed, s......

The interaction between lipocalin 2 and dipyridine ketone hydrazone dithiocarbamte may influence respective function in proliferation and metastasis-related gene expressions in HepG2 cell

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2021; 26 (1)

LCN2 (Lipocalins) was first identified as iron transporter through associating with its siderophores and also involved in many cancer metastases, but ......

Studies of anticancer activity in vivo and in vitro behaviors of liposomes encapsulated iridium(III) complex

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2021; 26 (1)

Iridium(III) complexes have gained great attention in cancer treatment in recent years. In this paper, we designed and synthesized a new iridium(III) ......

Comparison of (AlF)-F-18- and Ga-68-labeled NOTA-PEG(4)-LLP2A for PET imaging of very late antigen-4 in melanoma

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2020; 25 (1)

Malignant melanoma is an aggressive cancer with poor prognosis. Very late antigen-4 (VLA-4) is overexpressed in melanoma and many other tumors, making......

Study on the substitution effects of zinc benzoate terpyridine complexes on photoluminescence, antiproliferative potential and DNA binding properties

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2020; 25 (2)

Six zinc(II) complexes, [Zn(OCOPh)(2)L(R)] (R = 1, 2, 3, 4, 5, 6) were synthesized by the reaction of zinc benzoate and six para-substituted 4-phenyl-......

Mitochondria-targeted phosphorescent cyclometalated iridium(III) complexes: synthesis, characterization, and anticancer properties

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2020; 25 (4)

Cyclometalated iridium(III) complexes represent a promising approach to developing new anticancer metallodrugs. In this work, three phosphorescent cyc......

The oxidation of cyclo-olefin by the S=2 ground-state complex [Fe-IV(O)(TQA)(NCMe)](2+)

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2020; 25 (3)

Density functional theory calculation is used to investigate the oxidation of cyclo-olefin (cyclobutene, cyclopentene, cyclohexene, cycloheptene, and ......

Antibacterial activity of ruthenium polypyridyl complexes against Staphylococcus aureusand biofilms

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2020; 25 (5)

There is clearly a need for the development of new classes of antimicrobials to fight against multidrug-resistant bacteria. Here, we designed and synt......

Protein-bound calcium phosphate in uremic rat serum: a quantitative study

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2020; 25 (8)

Protein-bound calcium (prCa) constitutes about 40% of serum total calcium, in which albumin is the most dominant protein. Given the chemical interacti......

Evolutionary insights into the active-site structures of the metallo-beta-lactamase superfamily from a classification study with support vector machine

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2020; 25 (7)

The metallo-beta-lactamase (M beta L) superfamily, which is intriguing due to its enzyme promiscuity, is a good model enzyme superfamily for studies o......

Selenoprotein F knockout leads to glucose and lipid metabolism disorders in mice

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2020; 25 (7)

Selenoprotein F (Selenof), an endoplasmic reticulum (ER)-resident protein, is considered to be involved in glycoprotein folding and quality control in......

Biophysical insights into the interaction of two enantiomers of Ru(II) complex [Ru(bpy)(2)(7-CH3-dppz)](2+) with the RNA poly(U-A*U) triplex

期刊: JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 2020; 25 (8)

To determine the factors affecting the stabilization of RNA triple-stranded structure by chiral Ru(II) polypyridyl complexes, a new pair of enantiomer......

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