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Regulation of cell cycle drivers by Cullin-RING ubiquitin ligases

期刊: EXPERIMENTAL AND MOLECULAR MEDICINE, 2020; 52 (10)

The last decade has revealed new roles for Cullin-RING ubiquitin ligases (CRLs) in a myriad of cellular processes, including cell cycle progression. I......

SET8 suppression mediates high glucose-induced vascular endothelial inflammation via the upregulation of PTEN

期刊: EXPERIMENTAL AND MOLECULAR MEDICINE, 2020; 52 (10)

Hyperglycemia-mediated endothelial inflammation participates in the pathogenesis of cardiovascular complications in subjects with diabetes. Previous s......

A novel PPAR gamma ligand, PPZ023, overcomes radioresistance via ER stress and cell death in human non-small-cell lung cancer cells

期刊: EXPERIMENTAL AND MOLECULAR MEDICINE, 2020; 52 (10)

Peroxisome proliferator-activated receptor gamma (PPAR gamma) agonists exert powerful anticancer effects by suppressing tumor growth. In this study, w......

The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies

期刊: EXPERIMENTAL AND MOLECULAR MEDICINE, 2020; 52 (10)

TAR DNA-binding protein 43 (TDP-43) is a highly conserved nuclear RNA/DNA-binding protein involved in the regulation of RNA processing. The accumulati......

Evogliptin, a dipeptidyl peptidase-4 inhibitor, attenuates pathological retinal angiogenesis by suppressing vascular endothelial growth factor-induced Arf6 activation

期刊: EXPERIMENTAL AND MOLECULAR MEDICINE, 2020; 52 (10)

Retinal disease: How anti-diabetic drug can help eyes Pathological retinal angiogenesis, the damaging formation of new blood vessels in the retina, wh......

beta-catenin activates TGF-beta-induced epithelial-mesenchymal transition in adenomyosis

期刊: EXPERIMENTAL AND MOLECULAR MEDICINE, 2020; 52 (10)

Adenomyosis is defined as the presence of ectopic nests of endometrial glands and stroma within the myometrium. Adenomyosis is a common cause of dysme......

DYRK2 controls a key regulatory network in chronic myeloid leukemia stem cells

期刊: EXPERIMENTAL AND MOLECULAR MEDICINE, 2020; 52 (10)

Chronic myeloid leukemia is a hematological cancer driven by the oncoprotein BCR-ABL1, and lifelong treatment with tyrosine kinase inhibitors extends ......

Similar sequences but dissimilar biological functions of GDF11 and myostatin

期刊: EXPERIMENTAL AND MOLECULAR MEDICINE, 2020; 52 (10)

Growth factors: untangling twin proteins A growth factor protein called GDF11 has potential for rejuvenation of heart, brain, and muscle tissues, but ......

Formyl peptide receptors in the mucosal immune system

期刊: EXPERIMENTAL AND MOLECULAR MEDICINE, 2020; 52 (10)

Formyl peptide receptors: Receptors in the mucosal immune system Key receptors in defense against bacteria may also be attractive targets for diseases......

The impact of endotrophin on the progression of chronic liver disease

期刊: EXPERIMENTAL AND MOLECULAR MEDICINE, 2020; 52 (10)

Liver disease: Collagen fragment spurs liver inflammation and fibrosis Localized buildup in the liver of a collagen-derived cleavage fragment plays a ......

DNA end resection and its role in DNA replication and DSB repair choice in mammalian cells

期刊: EXPERIMENTAL AND MOLECULAR MEDICINE, 2020; 52 (10)

DNA repair: tying up loose ends Carefully regulated enzymatic processing of the ends of DNA strands is essential for efficient replication and damage ......

Apoptotic cell-derived exosomes: messages from dying cells

期刊: EXPERIMENTAL AND MOLECULAR MEDICINE, 2020; 52 (1)

Intercellular communication: dying cells send out messages Dying cells communicate with healthy cells through molecular messages contained in tiny mem......

Graft immaturity and safety concerns in transplanted human kidney organoids (vol 51, pg 1, 2019)

期刊: EXPERIMENTAL AND MOLECULAR MEDICINE, 2020; 52 (1)

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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