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Diabetes, metabolic disease, and telomere length

期刊: LANCET DIABETES & ENDOCRINOLOGY, 2021; 9 (2)

Telomeres are regions of repetitive nucleotide sequences at the ends of chromosomes. Telomere length is a marker of DNA damage, which is often conside......

Epidemiology and determinants of obesity in China

期刊: LANCET DIABETES & ENDOCRINOLOGY, 2021; 9 (6)

Obesity has become a major public health issue in China. Overweight and obesity have increased rapidly in the past four decades, and the latest nation......

Clinical management and treatment of obesity in China

期刊: LANCET DIABETES & ENDOCRINOLOGY, 2021; 9 (6)

China has one of the largest populations with obesity in the world, and obesity has become a major challenge for the country's health-care system. Cur......

Associations between body-mass index and COVID-19 severity in 6.9 million people in England: a prospective, community-based, cohort study

期刊: LANCET DIABETES & ENDOCRINOLOGY, 2021; 9 (6)

Background Obesity is a major risk factor for adverse outcomes after infection with SARS-CoV-2. We aimed to examine this association, including intera......

Obesity in China 3 Health policy and public health implications of obesity in China

期刊: LANCET DIABETES & ENDOCRINOLOGY, 2021; 9 (7)

China has experienced many drastic social and economic changes and shifts in people's lifestyles since the 1990s, in parallel with the fast rising pre......

Trends in the incidence of diagnosed diabetes: a multicountry analysis of aggregate data from 22 million diagnoses in high-income and middle-income settings

期刊: LANCET DIABETES & ENDOCRINOLOGY, 2021; 9 (4)

Background Diabetes prevalence is increasing in most places in the world, but prevalence is affected by both risk of developing diabetes and survival ......

Effects of dapagliflozin on major adverse kidney and cardiovascular events in patients with diabetic and non-diabetic chronic kidney disease: a prespecified analysis from the DAPA-CKD trial

期刊: LANCET DIABETES & ENDOCRINOLOGY, 2021; 9 (1)

Background Dapagliflozin reduces the risk of kidney failure and heart failure in patients with chronic kidney disease. We aimed to investigate the eff......

Smoking cessation and weight change in relation to cardiovascular disease incidence and mortality in people with type 2 diabetes: a population-based cohort study

期刊: LANCET DIABETES & ENDOCRINOLOGY, 2020; 8 (2)

Background To reduce their overall substantially increased risk of cardiovascular disease and premature mortality, smoking cessation is especially imp......

Association of insulin resistance and beta-cell dysfunction with incident diabetes among adults in China: a nationwide, population-based, prospective cohort study

期刊: LANCET DIABETES & ENDOCRINOLOGY, 2020; 8 (2)

Background National investigations on the interaction of insulin resistance, beta-cell dysfunction, and obesity with the development of diabetes are s......

Association of glucose-lowering medications with cardiovascular outcomes: an umbrella review and evidence map

期刊: LANCET DIABETES & ENDOCRINOLOGY, 2020; 8 (3)

Background Considering the global burden of diabetes and associated cardiovascular disease, an urgent need exists for the best treatment, which should......

Association of maternal thyroid function with birthweight: a systematic review and individual-participant data meta-analysis

期刊: LANCET DIABETES & ENDOCRINOLOGY, 2020; 8 (6)

Background Adequate transplacental passage of maternal thyroid hormone is important for normal fetal growth and development. Maternal overt hypothyroi......

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