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A two-part, single-arm, multicentre, phase I study of zanubrutinib, a selective Bruton tyrosine kinase inhibitor, in Chinese patients with relapsed/refractory B-cell malignancies

期刊: BRITISH JOURNAL OF HAEMATOLOGY, 2022; 198 (1)

This single-arm, multicentre, phase I study is the first study of zanubrutinib, a potent, specific, irreversible Bruton tyrosine kinase (BTK) inhibito......

JIF:2.626

Survival prediction optimization of acute myeloid leukaemia based on T-cell function-related genes and plasma proteins

期刊: BRITISH JOURNAL OF HAEMATOLOGY, 2022; 199 (4)

Interactions between acute myeloid leukaemia (AML) cells and immune cells are postulated to corelate with outcomes of AML patients. However, data on T......

JIF:2.626

Extended vincristine and dexamethasone pulse therapy may not be necessary for children with TCF3-PBX1 positive acute lymphoblastic leukaemia

期刊: BRITISH JOURNAL OF HAEMATOLOGY, 2022; 199 (4)

The effect of prolonged pulse therapy with vincristine and dexamethasone (VD) during maintenance therapy on the outcome of paediatric patients with TC......

JIF:2.626

Combination of PD-1 inhibitor with GVD (gemcitabine, vinorelbine, liposomal doxorubicin) versus GVD regimen as second-line therapy for relapsed/refractory classical Hodgkin lymphoma

期刊: BRITISH JOURNAL OF HAEMATOLOGY, 2022; 196 (1)

Patients with classical Hodgkin lymphoma (cHL) who do not achieve complete remission (CR) after second-line chemotherapy have poor clinical outcomes. ......

JIF:2.626

Significance of anti-HBc serological status in primary immune thrombocytopenia

期刊: BRITISH JOURNAL OF HAEMATOLOGY, 2022; 196 (4)

The association of previous hepatitis B virus (HBV) exposure [hepatitis B surface antigen (HBsAg) negative, hepatitis B core antibody (anti-HBc/HBcAb)......

JIF:2.626

Empagliflozin modulates CD4(+) T-cell differentiation via metabolic reprogramming in immune thrombocytopenia

期刊: BRITISH JOURNAL OF HAEMATOLOGY, 2022; 198 (4)

Immune thrombocytopenia (ITP) is an acquired autoimmune disease, in which the imbalance of CD4(+) T cell subsets play a key role in the pathogenesis. ......

JIF:2.626

Donor activating killer cell immunoglobulin-like receptors genes correlated with Epstein-Barr virus reactivation after haploidentical haematopoietic stem cell transplantation

期刊: BRITISH JOURNAL OF HAEMATOLOGY, 2022; 196 (4)

Natural killer (NK) cells exert anti-viral effects after haematopoietic stem cell transplantation (HSCT). The balance between inhibition and activatio......

JIF:2.626

Upregulation of HIF-1 alpha contributes to complement activation in transplantation-associated thrombotic microangiopathy

期刊: BRITISH JOURNAL OF HAEMATOLOGY, 2022; 199 (4)

Transplantation-associated thrombotic microangiopathy (TA-TMA) is a severe complication of haematopoietic stem cell transplantation (HSCT). Complement......

JIF:2.626

Intensified antiplatelet therapy in patients after percutaneous coronary intervention with high on-treatment platelet reactivity: the OPTImal Management of Antithrombotic Agents (OPTIMA)-2 Trial

期刊: BRITISH JOURNAL OF HAEMATOLOGY, 2022; 196 (2)

High on-treatment platelet reactivity (HOPR) is associated with increased risk of cardiovascular events in patients undergoing percutaneous coronary i......

JIF:2.626

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