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Evolution of Lung Cancer in the Context of Immunotherapy

期刊: CLINICAL MEDICINE INSIGHTS-ONCOLOGY, 2020; 14 ()

Immunotherapy, as a novel treatment, has brought new hope to many patients with cancer, including patients with lung cancer. However, the overall cure......

Genetic Heterogeneity Between Paired Primary and Brain Metastases in Lung Adenocarcinoma

期刊: CLINICAL MEDICINE INSIGHTS-ONCOLOGY, 2020; 14 ()

PURPOSE: About one-third of nonsmall cell lung cancer (NSCLC) patients develop brain metastases (BM). However, there is an unmet need for early diagno......

Combining Genetic Mutation and Expression Profiles Identifies Novel Prognostic Biomarkers of Lung Adenocarcinoma

期刊: CLINICAL MEDICINE INSIGHTS-ONCOLOGY, 2020; 14 ()

Motivation: Although several prognostic signatures for lung adenocarcinoma (LUAD) have been developed, they are mainly based on a single-omics data se......

A Diagnostic Nomogram of Pathologic Grade for Preoperative Risk Stratification in Upper Tract Urothelial Carcinoma

期刊: CLINICAL MEDICINE INSIGHTS-ONCOLOGY, 2020; 14 ()

Background: To develop a novel nomogram to improve the preoperative diagnosis of pathological grade of upper tract urothelial carcinoma (UTUC). Method......

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