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A prognostic nomogram based on competing endogenous RNA network for clear-cell renal cell carcinoma

期刊: CANCER MEDICINE, 2021; 10 (16)

Background Clear-cell renal cell carcinoma (ccRCC) is stubborn to traditional chemotherapy and radiation treatment, which makes its clinical managemen......

Comprehensive analysis of a new prognosis signature based on histone deacetylases in clear cell renal cell carcinoma

期刊: CANCER MEDICINE, 2021; 10 (18)

Histone deacetylases (HDAC) family is vital for tumorigenesis and tumor progression. However, the exact role of the HDAC family in clear cell renal ce......

First-line therapy of bevacizumab plus chemotherapy versus cetuximab plus chemotherapy for metastatic colorectal cancer patients with mucinous adenocarcinoma or mucinous component

期刊: CANCER MEDICINE, 2021; 10 (10)

Background To compare the efficacy of first-line bevacizumab plus chemotherapy with cetuximab plus chemotherapy based on the stratification of metasta......

Effectiveness and prognostic factors of apatinib treatment in patients with recurrent or advanced cervical carcinoma: A retrospective study

期刊: CANCER MEDICINE, 2021; 10 (13)

Background Apatinib is an oral anti-angiogenic drug, its efficacy and prognosis in cervical carcinoma are unclear. This study evaluates the effectiven......

The oncogenic role of the cerebral endothelial cell adhesion molecule (CERCAM) in bladder cancer cells in vitro and in vivo

期刊: CANCER MEDICINE, 2021; 10 (13)

Bladder cancer is a menace to global health worldwide due to its high recurrence rate and its progression to invasive muscular complications. Cell adh......

Global, regional and national incidence, mortality and disability-adjusted life-years of skin cancers and trend analysis from 1990 to 2019: An analysis of the Global Burden of Disease Study 2019

期刊: CANCER MEDICINE, 2021; 10 (14)

Background Information about global and local epidemiology and trends of skin cancers is limited, which increases the difficulty of cutaneous cancer c......

Estimating the risk of developing secondary hematologic malignancies in patients with T1/T2 prostate cancer undergoing diverse treatment modalities: A large population-based study

期刊: CANCER MEDICINE, 2021; 10 (15)

Background Patients with prostate cancer (PC) are at a high risk of developing secondary hematologic malignancies (SHMs) after radiation therapy (RT),......

Performance of cervical cancer screening and triage strategies among women living with HIV in China

期刊: CANCER MEDICINE, 2021; 10 (17)

Objectives To evaluate the clinical performance of liquid-based cytology (LBC), HPV tests and visual inspections with acetic acid or Lugol's iodine (V......

Clinicopathological and molecular characterizations of pulmonary NUT midline carcinoma

期刊: CANCER MEDICINE, 2021; 10 (17)

Introduction Pulmonary nuclear protein of the testis (NUT) midline carcinoma (NMC) is a aggressive cancer with t (15, 19) translocation. Here we prese......

DYRK1A activates NFATC1 to increase glioblastoma migration

期刊: CANCER MEDICINE, 2021; 10 (18)

Glioblastoma (GBM) is the most aggressive glioma, and is prone to develop resistance to chemotherapy and radiotherapy; hence, patients with glioblasto......

A novel five-gene signature predicts overall survival of patients with hepatocellular carcinoma

期刊: CANCER MEDICINE, 2021; 10 (11)

Hepatocellular carcinoma (HCC) is one of the most common public health challenges, worldwide. Because of molecular complexity and tumor heterogeneity,......

HHLA2 deficiency inhibits non-small cell lung cancer progression and THP-1 macrophage M2 polarization

期刊: CANCER MEDICINE, 2021; 10 (15)

Background Human endogenous retrovirus-H long terminal repeat-associating protein 2 (HHLA2) is a member of B7 family, which is upregulated in multiple......

EGFR-mutated stage IV non-small cell lung cancer: What is the role of radiotherapy combined with TKI?

期刊: CANCER MEDICINE, 2021; 10 (18)

Lung cancer is the leading cause of cancer-related death globally and poses a considerable threat to public health. Asia has the highest prevalence of......

A robust signature of immune-related long non-coding RNA to predict the prognosis of bladder cancer

期刊: CANCER MEDICINE, 2021; 10 (18)

Background Bladder cancer is the second most common malignant tumor in the urogenital system. The research investigated the prognostic role of immune-......

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