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Nonlinear relationship between visceral adiposity index and lung function: a population-based study

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Background As one of the critical indicators of obesity, the interaction between visceral fat content and lung disease is the focus of current researc......

Hydrogen/oxygen therapy for the treatment of an acute exacerbation of chronic obstructive pulmonary disease: results of a multicenter, randomized, double-blind, parallel-group controlled trial

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Background: To investigate whether the administration of hydrogen/oxygen mixture was superior to oxygen in improving symptoms in patients with acute e......

Family with sequence similarity 13 member A mediates TGF-beta 1-induced EMT in small airway epithelium of patients with chronic obstructive pulmonary disease

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Background: To explore the role of family with sequence similarity 13 member A (FAM13A) in TGF-beta 1-induced EMT in the small airway epithelium of pa......

SERPINB10 contributes to asthma by inhibiting the apoptosis of allergenic Th2 cells

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Background Serine peptidase inhibitor, clade B, member 10 (SERPINB10) contributes to allergic inflammation in asthma. However, its role in the T-helpe......

Risk factors for Pseudomonas aeruginosa colonization in non-cystic fibrosis bronchiectasis and clinical implications

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Background Pseudomonas aeruginosa is one of the commonest bacteria colonizing the airway in patients with non-cystic fibrosis bronchiectasis. Pseudomo......

Effects of diabetes on the development of radiation pneumonitis

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Radiation pneumonia (RP) is a common adverse reaction to radiation therapy in patients with chest tumors. Recent studies have shown that diabetes mell......

Idiopathic pulmonary fibrosis and diabetes mellitus: a meta-analysis and systematic review

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Background Idiopathic pulmonary fibrosis (IPF) is a chronic diffuse interstitial lung disease, of which the etiology has been poorly understood. Sever......

Pulmonary fibrosis and its related factors in discharged patients with new corona virus pneumonia: a cohort study

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Background Thousands of Coronavirus Disease 2019 (COVID-19) patients have been discharged from hospitals Persistent follow-up studies are required to ......

Mitochondrial creatine kinase 1 in non-small cell lung cancer progression and hypoxia adaptation

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Background Hypoxia is a prominent feature of solid cancer. This research aims to expose the role of mitochondrial creatine kinase 1 (CKMT1) in non-sma......

Development and performance assessment of novel machine learning models to predict pneumonia after liver transplantation

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Background: Pneumonia is the most frequently encountered postoperative pulmonary complications (PPC) after orthotopic liver transplantation (OLT), whi......

Effect of ambient fine particulates (PM2.5) on hospital admissions for respiratory and cardiovascular diseases in Wuhan, China

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Background Positive associations between ambient PM2.5 and cardiorespiratory disease have been well demonstrated during the past decade. However, few ......

Osimertinib alone as second-line treatment for brain metastases (BM) control may be more limited than for non-BM in advanced NSCLC patients with an acquired EGFR T790M mutation

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Background This study was designed to investigate the difference between brain metastases (BM) and non-brain metastases (non-BM) treated by osimertini......

TIPE2 inhibits PDGF-BB-induced phenotype switching in airway smooth muscle cells through the PI3K/Akt signaling pathway

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Background Childhood asthma is a common respiratory disease characterized by airway inflammation. Tumor necrosis factor-alpha-induced protein 8-like 2......

The modification effect of temperature on the relationship between air pollutants and daily incidence of influenza in Ningbo, China

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Background Although exposure to air pollution has been linked to many health issues, few studies have quantified the modification effect of temperatur......

Combined effects of lung disease history, environmental exposures, and family history of lung cancer to susceptibility of lung cancer in Chinese non-smokers

期刊: RESPIRATORY RESEARCH, 2021; 22 (1)

Background Although cigarette smoking is a major risk factor for lung cancer, the incidence rate of lung cancer among non-smokers is notable. The etio......

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