期刊： MOLECULAR CELL, 2022; 82 (24)
Maintenance of energy level to drive movements and material exchange with the environment is a basic prin-ciple of life. AMP-activated protein kinase ......
期刊： MOLECULAR CELL, 2022; 82 (24)
Programmed cell death and caspase proteins play a pivotal role in host innate immune response combating pathogen infections. Blocking cell death is em......
期刊： MOLECULAR CELL, 2021; 81 (7)
(G) proteins play a central role in signal transduction and pharmacology. Signaling is initiated by cell-surface receptors, which promote guanosine tr......
期刊： MOLECULAR CELL, 2021; 81 (9)
O-linked b-N-acetyl glucosamine (O-GlcNAc) is attached to proteins under glucose-replete conditions; this posttranslational modification results in mo......
期刊： MOLECULAR CELL, 2021; 81 (15)
Hershey and Chase used bacteriophage T2 genome delivery inside Escherichia coli to demonstrate that DNA, not protein, is the genetic material. Seventy......
期刊： MOLECULAR CELL, 2021; 81 (8)
Mediator is a universal adaptor for transcription control. It serves as an interface between gene-specific activator or repressor proteins and the gen......
期刊： MOLECULAR CELL, 2021; 81 (6)
The dopamine system, including five dopamine receptors (D1R-D5R), plays essential roles in the central nervous system (CNS), and ligands that activate......
期刊： MOLECULAR CELL, 2021; 81 (2)
The mechanisms of cellular energy sensing and AMPK-mediated mTORC1 inhibition are not fully delineated. Here, we discover that RIPK1 promotes mTORC1 i......
期刊： MOLECULAR CELL, 2021; 81 (14)
WhiB7 represents a distinct subclass of transcription factors in the WhiB-Like (Wbl) family, a unique group of iron-sulfur (4Fe-4S] cluster-containing......
期刊： MOLECULAR CELL, 2021; 81 (15)
OTULIN coordinates with LUBAC to edit linear polyubiquitin chains in embryonic development, autoimmunity, and inflammatory diseases. However, the mech......
期刊： MOLECULAR CELL, 2021; 81 (8)
The coactivator p300/CREB-binding protein (CBP) regulates genes by facilitating the assembly of transcriptional machinery and by acetylating histones ......
期刊： MOLECULAR CELL, 2021; 81 (1)
Among the five KCNQ channels, also known as the K(v)7 voltage-gated potassium (K-v) channels, KCNQ2-KCNQ5 control neuronal excitability. Dysfunctions ......
期刊： MOLECULAR CELL, 2021; 81 (7)
Using a forward-genetic screening of macrophages from randomly mutagenized mice, Kayagaki et al. (2021) identify NINJ1 that mediates plasma membrane r......
期刊： MOLECULAR CELL, 2021; 81 (12)
Posttranslational modification (PTM), through the recruitment of effector proteins (i.e., "readers") that signal downstream events, plays key roles in......
期刊： MOLECULAR CELL, 2021; 81 (5)
STING-dependent cytosolic DNA sensing in dendritic cells (DCs) initiates antitumor immune responses, but how STING signaling is metabolically regulate......
