期刊： AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2021; 65 (3)
Inflammasomes are intracellular multiprotein complexes that help trigger and maintain the inflammatory response as part of the innate immune system. R......
期刊： AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2021; 65 (1)
Acute respiratory infections caused by influenza A virus (IAV) spread widely and lead to substantial morbidity and mortality. Host cell induction of t......
期刊： AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2021; 65 (2)
Strict control of iron homeostasis is critical for the maintenance of normal lung function. Iron accumulates in the lungs of patients with idiopathic ......
期刊： AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2021; 65 (3)
Endothelial dysfunction is implicated in the thrombotic events reported in patients with coronavirus disease (COVID-19), but the underlying molecular ......
期刊： AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2021; 64 (6)
Smoking-mediated reprogramming of the phenotype and function of airway basal cells (BCs) disrupts airway homeostasis and is an early event in chronic ......
期刊： AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2021; 64 (5)
Skeletal muscle dysfunction is one of the important comorbidities of chronic obstructive pulmonary disease (COPD); however, the underlying mechanisms ......
期刊： AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2021; 65 (2)
Macrophages undergo profound metabolic reprogramming to join key immunoregulatory functions, which can be initiated by pattern recognition receptors. ......
期刊： AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2021; 65 (1)
Pulmonary fibrosis is a progressive and fatal lung disease characterized by activation of lung fibroblasts and excessive deposition of collagen matrix......
期刊： AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2021; 64 (5)
Community-acquired pneumonia is the most common type of pneumonia and remains a leading cause of morbidity and mortality worldwide. Although many diff......
期刊： AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2021; 64 (1)
Augmented glycolysis due to metabolic reprogramming in lung myofibroblasts is critical to their profibrotic phenotype. The primary glycolysis byproduc......
期刊： AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2021; 64 (1)
A history of chronic cigarette smoking is known to increase risk for acute respiratory distress syndrome (ARDS), but the corresponding risks associate......
期刊： AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2021; 64 (2)
Acute respiratory distress syndrome (ARDS) is a critical condition with high mortality. HMGB1 (high-mobility group protein B1) is one of the key proin......
期刊： AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2021; 64 (3)
Pulmonary angiogenesis is a key driver of alveolarization. Our prior studies showed that NF-kappa B promotes pulmonary angiogenesis during early alveo......
