期刊: BIOINFORMATICS, 2022; 38 (2)
Motivation: Alternative splicing contributes to the diversity of RNA found in biological samples. Current tools investigating patterns of alternative ......
期刊: BIOINFORMATICS, 2023; 39 (1)
Motivation: The gut microbiome changes rapidly under the influence of different factors such as age, dietary changes or medications to name just a few......
期刊: BIOINFORMATICS, 2023; 39 (1)
Sequence homology is a basic concept in protein evolution, structure and function studies. However, there are not many different tools and services fo......
期刊: BIOINFORMATICS, 2023; 39 (1)
Biological condensates are membraneless organelles with different material properties. Proteins and RNAs are the main components, but most of their in......
期刊: BIOINFORMATICS, 2023; 39 (1)
Motivation: Identifying appropriate pharmacotherapy options from genomics results is a significant challenge in personalized oncology. However, comput......
期刊: BIOINFORMATICS, 2023; 39 (4)
Motivation: Feature-based counting is commonly used in RNA-sequencing (RNA-seq) analyses. Here, sequences must align to target features (like genes or......
期刊: BIOINFORMATICS, 2023; 39 (4)
Motivation This work is motivated by the problem of identifying homozygosity islands on the genome of individuals in a population. Our method directly......
期刊: BIOINFORMATICS, 2023; 39 (6)
Motivation: The generation of parameter files for molecular dynamics (MD) simulations of small molecules that are suitable for force fields commonly a......
期刊: BIOINFORMATICS, 2023; 39 (6)
Biomedical named entity recognition (NER) plays a crucial role in extracting information from documents in biomedical applications. However, many of t......
期刊: BIOINFORMATICS, 2023; 39 ()
Motivation: The size of available omics datasets is steadily increasing with technological advancement in recent years. While this increase in sample ......
期刊: BIOINFORMATICS, 2023; 39 (7)
Motivation Biomarker discovery is one of the most frequent pursuits in bioinformatics and is crucial for precision medicine, disease prognosis, and dr......
期刊: BIOINFORMATICS, 2023; 39 (7)
Summary Biological pattern formation is one of the complex system phenomena in nature, requiring theoretical analysis based on mathematical modeling a......
期刊: BIOINFORMATICS, 2023; 39 (8)
Motivation: Open Target Genetics is a comprehensive resource portal that offers variant-centric statistical evidence, enabling the prioritization of c......
期刊: BIOINFORMATICS, 2023; 39 (10)
Motivation Biological network analysis for high-throughput biomedical data interpretation relies heavily on topological characteristics. Networks are ......