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One-off low-dose CT for lung cancer screening in China: a multicentre, population-based, prospective cohort study

期刊: LANCET RESPIRATORY MEDICINE, 2022; 10 (4)

Background Lung cancer is the leading cause of cancer death worldwide. Data on the effectiveness of one-off low-dose CT (LDCT) in reducing lung cancer......

Health outcomes in people 2 years after surviving hospitalisation with COVID-19: a longitudinal cohort study

期刊: LANCET RESPIRATORY MEDICINE, 2022; 10 (9)

Background With the ongoing COVID-19 pandemic, growing evidence shows that a considerable proportion of people who have recovered from COVID-19 have l......

Safety and immunogenicity of a live-attenuated influenza virus vector-based intranasal SARS-CoV-2 vaccine in adults: randomised, double-blind, placebo-controlled, phase 1 and 2 trials

期刊: LANCET RESPIRATORY MEDICINE, 2022; 10 (8)

Background All currently available SARS-CoV-2 vaccines are administered by intramuscular injection. We aimed to evaluate the safety and immunogenicity......

Icotinib versus chemotherapy as adjuvant treatment for stage II-IIIA EGFR-mutant non-small-cell lung cancer (EVIDENCE): a randomised, open-label, phase 3 trial

期刊: LANCET RESPIRATORY MEDICINE, 2021; 9 (9)

Background Icotinib has provided survival benefits for patients with advanced, epidermal growth factor receptor (EGFR)-mutant non-small-cell lung canc......

3-month, 6-month, 9-month, and 12-month respiratory outcomes in patients following COVID-19-related hospitalisation: a prospective study

期刊: LANCET RESPIRATORY MEDICINE, 2021; 9 (7)

Background The consequences of COVID-19 in those who recover from acute infection requiring hospitalisation have yet to be clearly defined. We aimed t......

Efficacy, safety, and genetic analysis of furmonertinib (AST2818) in patients with EGFR T790M mutated non-small-cell lung cancer: a phase 2b, multicentre

期刊: LANCET RESPIRATORY MEDICINE, 2021; 9 (8)

Background Furmonertinib (AST2818) is a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) targeting both sensit......

Association between pre-existing respiratory disease and its treatment, and severe COVID-19: a population cohort study

期刊: LANCET RESPIRATORY MEDICINE, 2021; 9 (8)

Background Previous studies suggested that the prevalence of chronic respiratory disease in patients hospitalised with COVID-19 was lower than its pre......

Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019 a systematic analysis for the Global Burden of Disease Study 2019

期刊: LANCET RESPIRATORY MEDICINE, 2021; 9 (9)

Background Prevention, control, and treatment of respiratory tract cancers are important steps towards achieving target 3.4 of the UN Sustainable Deve......

Effect of a single day of increased as-needed budesonide-formoterol use on short-term risk of severe exacerbations in patients with mild asthma: a post-hoc analysis of the SYGMA 1 study

期刊: LANCET RESPIRATORY MEDICINE, 2021; 9 (2)

Background In mild asthma, as-needed budesonide-formoterol reduces long-term exacerbation risk compared with as-needed short-acting beta(2)-agonist (S......

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