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An Overview on Immunity Booster Foods in Coronavirus Disease (COVID-19)

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023; 26 (7)

The present COVID-19 pandemic is terrible for the respiratory system and is caused by severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). It......

Application of Machine Learning in Rheumatoid Arthritis Diseases Research: Review and Future Directions

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023; 26 (13)

Rheumatoid arthritis (RA) is a chronic, destructive condition that affects and destroys the joints of the hand, fingers, and legs. Patients may forfei......

Natural Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors: A Review

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023; 26 (15)

PCSK9 (proprotein convertase subtilisin/kexin type 9) is an enzyme that helps to reduce cardiovascular events. This clinical result is attributable pr......

Design, Synthesis, and Anti-Cancer Activity Evaluation of a 3-methy-leneisoindolin-1-One Library

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023; 26 (9)

Background Isoindolin-1-ones are medicinally privileged heterocyclic compounds. Due to the interesting biological activities exhibited by these compou......

Investigating Biological Properties of Zinc Oxide/Curcumin Nanocomposites Synthesized from Stachys byzantina Extract by Green Synthesis

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023; 26 (3)

Aim and Objective Nanotechnology attempts to solve the problem of antibiotic resistance. Zinc oxide nanoparticles and curcumin have been shown to be a......

Potential of 24-Propylcholestrol as Immunity Inducer against Infection of COVID-19 Virus: In Silico Study Immunomodulatory Drugs

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023; 26 (2)

Background: COVID-19 (Coronavirus Disease 2019) caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) has infected millions of people......

Synthesis, Drug-Likeness Evaluation of Some Heterocyclic Moieties Fused Indole Derivatives as Potential Antioxidants

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023; 26 (11)

Background Indole and its derivatives have a wide range of pharmacological effects, including analgesic, antimicrobial, antidepressant, anti-diabetic,......

Appraising the Phytochemical and Therapeutic Perspectives of Bryonia laciniosa: A Literature Metasynthesis

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023; 26 (7)

Background Nature has bestowed mother Earth with an array of herbals utilized as therapeutics for various human ailments since the origin of life. Bry......

Nigella sativa Oil Alleviates Mouse Testis and Sperm Abnormalities Induced by BPA Potentially through Redox Homeostasis

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023; 26 (2)

Background & Aim: Significant evidence indicates that endocrine disrupted bisphenol A (BPA) seriously endangers human health. In males, BPA affect......

Insights into the Structural Complexities of SARS-CoV-2 for Therapeutic and Vaccine Development

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023; 26 (11)

SARS-CoV-2 is a disease that endangers both human life and the economy. There was an 11-month period of relative evolutionary standstill following the......

Understanding the Artemia Salina (Brine Shrimp) Test: Pharmacological Significance and Global Impact

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023; ()

Background: The microplate benchtop brine shrimp test (BST) has been widely used for screening and bio-guided isolation of many active compounds, incl......

Evaluation of the Nimbamrithadhi Panchathiktha Kashayam against SARS CoV-2 based on Network Pharmacology and Molecular Docking analysis

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023; 26 (2)

Background: Nimbamrithadhi Panchathiktha Kashayam (NPK) is an Ayurvedic formulation of potent plant ingredients with immune-modulating effects and ant......

Natural Cycloartane Triterpenoids from Corypha utan Lamk. with Anticancer Activity towards P388 Cell Lines and their Predicted Interaction with FLT3

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023; 26 (13)

Background Cancer is the second leading cause of death in the world. Leukemia is a type of cancer that accounts for 31.5% of all cancers in children u......

Chiral Inversion of Pharmaceutical Drugs - Mini Review

期刊: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2023; 26 (15)

2-Arylpropionic acid nonsteroidal anti-inflammatory drugs (NSAIDs) provide one of the most demonstrated pharmaceutical examples of chiral inversion. C......

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