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miR-122-5p targets GREM2 to protect against glucocorticoid-induced endothelial damage through the BMP signaling pathway

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 544 ()

Glucocorticoid (GC)-induced osteonecrosis of the femoral head (ONFH) accounts for a big portion of non traumatic ONFH; nevertheless, the pathogenesis ......

JIF:3.76

Autophagy protects against high uric acid-induced hepatic insulin resistance

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 547 ()

Uric acid (UA), the end-product of purine metabolism, is closely related to hepatic insulin resistance (IR). Autophagy is a conserved intracellular de......

JIF:3.76

Activation of estrogen receptor ESR1 and ESR2 induces proliferation of the human testicular embryonal carcinoma NT2/D1 cells

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 554 ()

The aims of the present study were to investigate the expression of the classic estrogen receptors ESR1 and ESR2, the splicing variant ESR1-36 and GPE......

JIF:3.76

FSH inhibits autophagy and lysosomal biogenesis to regulate protein degradation in cultured goat Sertoli cells

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 540 ()

Although the follicle-stimulating hormone (FSH) plays a vital role in male reproduction, the molecular relationships among FSH, autophagy, and the sec......

JIF:3.76

Ceramide signaling in the gut

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 544 ()

Sphingolipids are essential lipid components in the intestinal epithelial cells (IEC) along the intestinal tract. They play crucial roles in maintaini......

JIF:3.76

Tanshinone IIA and its derivative activate thermogenesis in adipocytes and induce beiging of white adipose tissue

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 544 ()

Tanshinone IIA (TAN2A) is a major active ingredient of Salvia miltiorrhiza used in traditional Chinese medicine and tanshinone 20 (TAN20) is a derivat......

JIF:3.76

Noradrenaline and ATP regulate adiponectin exocytosis in white adipocytes: Disturbed adrenergic and purinergic signalling in obese and insulin-resistant mice

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 549 ()

White adipocyte adiponectin exocytosis is triggered by cAMP and a concomitant increase of cytosolic Ca2+ potentiates its release. White adipose tissue......

JIF:3.76

Bergamot leaf extract treats cardiorenal metabolic syndrome and associated pathophysiological factors in rats fed with a high sugar fat diet

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 556 ()

Bergamot citrus (Citrus bergamia Risso et Poiteau), have been used as a strategy to prevent or treat comorbidities associated with metabolic syndrome ......

JIF:3.76

Interactive effects of anthropogenic environmental drivers on endocrine responses in wildlife

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 556 ()

Anthropogenic activity has created unique environmental drivers, which may interact to produce unexpected effects. My aim was to conduct a systematic ......

JIF:3.76

Combinational exposure to Bisphenol A and a high-fat diet causes trans-generational Malfunction of the female reproductive system in mice

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 541 ()

Bisphenol A (BPA) is a common endocrine disruptor and a high-fat diet (HFD) also affects fertility. However, little is known about the long-term conse......

JIF:3.76

Treatment with spexin mitigates diet-induced hepatic steatosis in vivo and in vitro through activation of galanin receptor 2

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 552 ()

It was reported that spexin as an adipocyte-secreted protein could regulate obesity and insulin resistance. However, the specific metabolic contributi......

JIF:3.76

Sitagliptin reduces FAP-activity and increases intact FGF21 levels in patients with newly detected glucose abnormalities

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 556 ()

Introduction: Fibroblast growth factor 21 (FGF21), a hormone with pleiotropic metabolic effects, is inactivated by fibroblast activation protein (FAP)......

JIF:3.76

Vitamin C protects against hypoxia, inflammation, and ER stress in primary human preadipocytes and adipocytes

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 556 ()

Dysregulation of adipose tissue involves increased cellular hypoxia, ER stress, and inflammation and altered adipokine production, contributing to the......

JIF:3.76

Overexpression of estrogen receptor GPER1 and G1 treatment reduces SARS-CoV-2 infection in BEAS-2B bronchial cells

期刊: MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2022; 558 ()

Gender-bias in COVID-19 severity has been suggested by clinical data. Experimental data in cell and animal models have demonstrated the role of sex ho......

JIF:3.76

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