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An updated view on the centrosome as a cell cycle regulator

期刊: CELL DIVISION, 2022; 17 (1)

The centrosome is a multifunctional organelle that is known primarily for its microtubule organising function. Centrosomal defects caused by changes i......

JIF:4.667

dGLYAT modulates Gadd45-mediated JNK activation and cell invasion

期刊: CELL DIVISION, 2022; 17 (1)

Background Cell invasion is a crucial step of tumor metastasis, finding new regulators of which offers potential drug targets for cancer therapy. Aber......

JIF:4.667

The genomic stability regulator PTIP is required for proper chromosome segregation in mitosis

期刊: CELL DIVISION, 2022; 17 (1)

Background The Pax transcription activation domain-interacting protein (PTIP) is a nuclear protein that is an essential component of H3K4 methylation ......

JIF:4.667

Ral GTPase is essential for actin dynamics and Golgi apparatus distribution in mouse oocyte maturation

期刊: CELL DIVISION, 2021; 16 (1)

Background Ral family is a member of Ras-like GTPase superfamily, which includes RalA and RalB. RalA/B play important roles in many cell biological fu......

Microarray expression profile of mRNAs and long noncoding RNAs and the potential role of PFK-1 in infantile hemangioma

期刊: CELL DIVISION, 2021; 16 (1)

Background: Infantile hemangioma (IH) is the most common benign tumor in children. Long noncoding RNAs (lncRNAs) play a critical role in tumorigenesis......

Chromosomal aberration arises during somatic reprogramming to pluripotent stem cells

期刊: CELL DIVISION, 2020; 15 (1)

Background Reprogramming somatic cells to induced pluripotent stem cells (iPSCs) has opened new therapeutic possibilities. However, karyotypic abnorma......

A positive feedback loop between EZH2 and NOX4 regulates nucleus pulposus cell senescence in age-related intervertebral disc degeneration

期刊: CELL DIVISION, 2020; 15 (1)

Background The senescence of nucleus pulposus (NP) cells plays a vital role in the pathogenesis of intervertebral disc (IVD) degeneration (IDD). NADPH......

IGFBP5 increases cell invasion and inhibits cell proliferation by EMT and Akt signaling pathway in Glioblastoma multiforme cells

期刊: CELL DIVISION, 2020; 15 (1)

Background Recurrence of Glioblastoma multiforme (GBM) seems to be the rule despite combination therapies. Cell invasion and cell proliferation are ma......

Kinesin-5 Eg5 is essential for spindle assembly and chromosome alignment of mouse spermatocytes

期刊: CELL DIVISION, 2020; 15 (1)

Background Microtubule organization is essential for bipolar spindle assembly and chromosome segregation, which contribute to genome stability. Kinesi......

Toll signaling promotes JNK-dependent apoptosis in Drosophila

期刊: CELL DIVISION, 2020; 15 (1)

Background Apoptosis plays pivotal roles in organ development and tissue homeostasis, with its major function to remove unhealthy cells that may compr......

EZH2-inhibitor DZNep enhances apoptosis of renal tubular epithelial cells in presence and absence of cisplatin

期刊: CELL DIVISION, 2020; 15 (1)

Background The enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase and induces the trimethylation of histone H3 lysine 27 (H3K27me3) in ......

Overexpression of P16 reversed the MDR1-mediated DDP resistance in the cervical adenocarcinoma by activating the ERK1/2 signaling pathway

期刊: CELL DIVISION, 2019; 14 ()

BackgroundTo investigate the role of P16 (INK4a)-extracellular signal related kinase 1/2 (ERK1/2) signaling pathway in cisplatin (DDP) resistance indu......

JIF:4.06

Septin and Ras regulate cytokinetic abscission in detached cells

期刊: CELL DIVISION, 2019; 14 (1)

Background Integrin-mediated adhesion is normally required for cytokinetic abscission, and failure in the process can generate potentially oncogenic t......

JIF:4.06

Subunits of human condensins are potential therapeutic targets for cancers

期刊: CELL DIVISION, 2018; 13 ()

The main role of condensins is to regulate chromosome condensation and segregation during cell cycles. Recently, it has been suggested in the literatu......

JIF:4.06

Kif18a regulates Sirt2-mediated tubulin acetylation for spindle organization during mouse oocyte meiosis

期刊: CELL DIVISION, 2018; 13 ()

BackgroundDuring oocyte meiosis, the cytoskeleton dynamics, especially spindle organization, are critical for chromosome congression and segregation. ......

JIF:4.06

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