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Physical exercise improves mitochondrial function in ovariectomized rats

期刊: JOURNAL OF ENDOCRINOLOGY, 2022; 254 (2)

Estrogen deficiency causes metabolic disorders in humans and rodents, including in part due to changes in energy expenditure. We have shown previously......

JIF:4.051

mTOR inhibitor improves testosterone-induced myocardial hypertrophy in hypertensive rats

期刊: JOURNAL OF ENDOCRINOLOGY, 2022; 252 (3)

Compelling evidence has described that the incidence of hypertension and left ventricular hypertrophy (LVH) in postmenopausal women is significantly i......

JIF:4.051

Physiological levels of estradiol limit murine osteoarthritis progression

期刊: JOURNAL OF ENDOCRINOLOGY, 2022; 255 (2)

Among patients with knee osteoarthritis (OA), postmenopausal women are over-represented. The purpose of this study was to determine whether deficiency......

JIF:4.051

AKR1D1 knockout mice develop a sex-dependent metabolic phenotype

期刊: JOURNAL OF ENDOCRINOLOGY, 2022; 253 (3)

Steroid 5 beta-reductase (AKR1D1) plays important role in hepatic bile acid synthesis and glucocorticoid clearance. Bile acids and glucocorticoids are......

JIF:4.051

A tissue-specific role of membrane-initiated ER alpha signaling for the effects of SERMs

期刊: JOURNAL OF ENDOCRINOLOGY, 2022; 253 (2)

Selective estrogen receptor modulators (SERMs) act as estrogen receptor (ER) agonists or antagonists in a tissue-specific manner. ERs exert effects vi......

JIF:4.051

Adiponectin regulates the circadian rhythm of glucose and lipid metabolism

期刊: JOURNAL OF ENDOCRINOLOGY, 2022; 254 (2)

Adiponectin is a cytokine secreted from adipocytes and regulates metabolism. Although serum adiponectin levels show diurnal variations, it is not clea......

JIF:4.051

Thyroid hormone regulators in human cerebral cortex development

期刊: JOURNAL OF ENDOCRINOLOGY, 2022; 255 (3)

Brain development is critically dependent on the timely supply of thyroid hormones. The thyroid hormone transporters are central to the action of thyr......

JIF:4.051

Fetal resorption coincides with dysregulated LH secretion in AMH-overexpressing mice

期刊: JOURNAL OF ENDOCRINOLOGY, 2022; 253 (2)

Female anti-Mullerian hormone (AMH) overexpressing (Thy1.2-AMH(Tg/0)) mice experience fetal resorption (miscarriage) by mid-gestation. This study exam......

JIF:4.051

Increased osteoblast Ga-S level determines bone response to hyperparathyroidism in female mice

期刊: JOURNAL OF ENDOCRINOLOGY, 2022; 254 (1)

G(S), the stimulatory heterotrimeric G protein, is an essential regulator of osteogenesis and bone turnover. To determine if increasing G alpha(S) in ......

JIF:4.051

Exogenous cholesterol acquisition signaling in LH-responsive MA-10 Leydig cells and in adult mice

期刊: JOURNAL OF ENDOCRINOLOGY, 2022; 254 (3)

MA-10 cells, established 4 decades ago from a murine Leydig cell tumor, has served as a key model system for studying steroidogenesis. Despite a preci......

JIF:4.051

Intrauterine malnutrition disrupts leptin and ghrelin milk hormones, programming rats

期刊: JOURNAL OF ENDOCRINOLOGY, 2022; 255 (1)

Herein, we assessed milk hormones, the biochemical composition of milk, and its association with neonatal body weight gain and metabolic homeostasis i......

JIF:4.051

Histidine decarboxylase inhibitors: a novel therapeutic option for the treatment of leydigioma

期刊: JOURNAL OF ENDOCRINOLOGY, 2022; 255 (3)

Recent reports indicate an increase in Leydig cell tumor (LCT) incidence. Radical orchiectomy is the standard therapy in children and adults, although......

JIF:4.051

Dapagliflozin partially restores reproductive function in MC4R KO obese female mice

期刊: JOURNAL OF ENDOCRINOLOGY, 2022; 254 (2)

Obese women often have certain degree of reproductive dysfunction with infertility. Although the clinical impact of obesity on female infertility has ......

JIF:4.051

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