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Vasodilatory Actions of Glucagon-Like Peptide 1 Are Preserved in Skeletal and Cardiac Muscle Microvasculature but Not in Conduit Artery in Obese Humans With Vascular Insulin Resistance

期刊: DIABETES CARE, 2020; 43 (3)

OBJECTIVE Obesity is associated with microvascular insulin resistance, which is characterized by impaired insulin-mediated microvascular recruitment. ......

Distinct Growth Phases in Early Life Associated With the Risk of Type 1 Diabetes: The TEDDY Study

期刊: DIABETES CARE, 2020; 43 (3)

OBJECTIVE This study investigates two-phase growth patterns in early life and their association with development of islet autoimmunity (IA) and type 1......

Establishment and Validation of a Risk Prediction Model for Early Diabetic Kidney Disease Based on a Systematic Review and Meta-Analysis of 20 Cohorts

期刊: DIABETES CARE, 2020; 43 (4)

BACKGROUND Identifying patients at high risk of diabetic kidney disease (DKD) helps improve clinical outcome. PURPOSE To establish a model for predict......

Dietary Nonheme, Heme, and Total Iron Intake and the Risk of Diabetes in Adults: Results From the China Health and Nutrition Survey

期刊: DIABETES CARE, 2020; 43 (4)

OBJECTIVE Excessive iron intake has been linked to diabetes risk. However, the evidence is inconsistent. This study examined the association between d......

Glucosamine Use, Inflammation, and Genetic Susceptibility, and Incidence of Type 2 Diabetes: A Prospective Study in UK Biobank

期刊: DIABETES CARE, 2020; 43 (4)

OBJECTIVE Glucosamine is a widely used supplement typically taken for osteoarthritis and joint pain. Emerging evidence suggests potential links of glu......

Trends in Bone Mineral Density, Osteoporosis, and Osteopenia Among US Adults With Prediabetes, 2005-2014

期刊: DIABETES CARE, 2020; 43 (5)

OBJECTIVE We aimed to evaluate trends in bone mineral density (BMD) and the prevalence of osteoporosis/osteopenia in U.S. adults with prediabetes and ......

Wilson Disease With Novel Compound Heterozygote Mutations in the ATP7B Gene Presenting With Severe Diabetes

期刊: DIABETES CARE, 2020; 43 (6)

OBJECTIVE To determine the relationship between ATP7B mutations and diabetes in Wilson disease (WD). RESEARCH DESIGN AND METHODS A total of 21 exons a......

Dietary Manganese, Plasma Markers of Inflammation, and the Development of Type 2 Diabetes in Postmenopausal Women: Findings From the Women's Health Initiative

期刊: DIABETES CARE, 2020; 43 (6)

OBJECTIVE To examine the association between manganese intake and the risk of type 2 diabetes in postmenopausal women and determine whether this assoc......

Effects of Intensive Glycemic Control on Clinical Outcomes Among Patients With Type 2 Diabetes With Different Levels of Cardiovascular Risk and Hemoglobin A(1c) in the ADVANCE Trial

期刊: DIABETES CARE, 2020; 43 (6)

OBJECTIVE To study whether the effects of intensive glycemic control on major vascular outcomes (a composite of major macrovascular and major microvas......

Circulating Retinol-Binding Protein 4 Is Inversely Associated With Pancreatic beta-Cell Function Across the Spectrum of Glycemia

期刊: DIABETES CARE, 2020; 43 (6)

OBJECTIVE The aim of this study was to examine the association of circulating retinol-binding protein 4 (RBP4) levels with beta-cell function across t......

Prognostic Significance of Long-term HbA(1c) Variability for All-Cause Mortality in the ACCORD Trial

期刊: DIABETES CARE, 2020; 43 (6)

OBJECTIVE The association between high glycemic variability and all-cause mortality has been widely investigated in epidemiological studies but rarely......

Contrasting Associations Between Diabetes and Cardiovascular Mortality Rates in Low-, Middle-, and High-Income Countries: Cohort Study Data From 143,567 Individuals in 21 Countries in the PURE Study

期刊: DIABETES CARE, 2020; 43 (12)

OBJECTIVE We aimed to compare cardiovascular (CV) events, all-cause mortality, and CV mortality rates among adults with and without diabetes in countr......

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