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Comprehensive Analysis of Differential m6A RNA Methylomes in the Hippocampus of Cocaine-Conditioned Mice

期刊: MOLECULAR NEUROBIOLOGY, 2021; 58 (8)

N6-methyladenosine (m6A) is the most prevalent internal modification found in mRNAs and lncRNA and plays a vital role in posttranscriptional regulatio......

Infliximab Can Improve Traumatic Brain Injury by Suppressing the Tumor Necrosis Factor Alpha Pathway

期刊: MOLECULAR NEUROBIOLOGY, 2021; 58 (6)

Traumatic brain injury (TBI) has both high morbidity and mortality rates and can negatively influence physical and mental health, while also causing e......

The mTOR/NF-kappa B Pathway Mediates Neuroinflammation and Synaptic Plasticity in Diabetic Encephalopathy

期刊: MOLECULAR NEUROBIOLOGY, 2021; 58 (8)

Diabetic encephalopathy, a severe complication of diabetes mellitus, is characterized by neuroinflammation and aberrant synaptogenesis in the hippocam......

New Insights into the Role of Ferritin in Iron Homeostasis and Neurodegenerative Diseases

期刊: MOLECULAR NEUROBIOLOGY, 2021; 58 (6)

Growing evidence has indicated that iron deposition is one of the key factors leading to neuronal death in the neurodegenerative diseases. Ferritin is......

Exploring the Genetic Association of the ABAT Gene with Alzheimer's Disease

期刊: MOLECULAR NEUROBIOLOGY, 2021; 58 (5)

Accumulating evidence demonstrated that GABAergic dysfunction contributes to the pathogenesis of Alzheimer's disease (AD). The GABA aminotransferase (......

Interleukin 17A Derived from gamma delta T Cell Induces Demyelination of the Brain in Angiostrongylus cantonensis Infection

期刊: MOLECULAR NEUROBIOLOGY, 2021; 58 (8)

Angiostrongylus cantonensis infection is a typical cause of eosinophilic encephalitis (EM), which has been reported to induce serious damage in the ce......

The Protective A673T Mutation of Amyloid Precursor Protein (APP) in Alzheimer's Disease

期刊: MOLECULAR NEUROBIOLOGY, 2021; 58 (8)

Alzheimer's disease is a progressive neurodegenerative disorder characterized by extracellular amyloid beta peptides and neurofibrillary tangles consi......

Oxiracetam Mediates Neuroprotection Through the Regulation of Microglia Under Hypoxia-Ischemia Neonatal Brain Injury in Mice

期刊: MOLECULAR NEUROBIOLOGY, 2021; 58 (8)

In neonatal hypoxic-ischemic brain damage (HIBD), in addition to damage caused by hypoxia and ischemia, over-activation of inflammation leads to furth......

Targeted sequencing and integrative analysis to prioritize candidate genes in neurodevelopmental disorders

期刊: MOLECULAR NEUROBIOLOGY, 2021; 58 (8)

Neurodevelopmental disorders (NDDs) are a group of diseases characterized by high heterogeneity and frequently co-occurring symptoms. The mutational s......

Proteomic and Transcriptomic Analyses Reveal Pathological Changes in the Entorhinal Cortex Region that Correlate Well with Dysregulation of Ion Transport in Patients with Alzheimer's Disease

期刊: MOLECULAR NEUROBIOLOGY, 2021; 58 (8)

Alzheimer's disease (AD) is the most common neurodegenerative disorder. The earliest neuropathology of AD appears in entorhinal cortex (EC) regions. T......

Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2

期刊: MOLECULAR NEUROBIOLOGY, 2021; 58 (8)

Specification of the progenitors' regional identity is a pivotal step during development of the cerebral cortex and basal ganglia. The molecular mecha......

COVID-19 Infection and Circulating Microparticles-Reviewing Evidence as Microthrombogenic Risk Factor for Cerebral Small Vessel Disease

期刊: MOLECULAR NEUROBIOLOGY, 2021; 58 (8)

Severe acute respiratory syndrome corona virus-2 (SARS-CoV-2) due to novel coronavirus disease 2019 (COVID-19) has affected the global society in nume......

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