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Weekly and seasonal variation in the circadian melatonin rhythm in humans: A response

期刊: JOURNAL OF PINEAL RESEARCH, 2022; 72 (1)

We read with interest the commentary by Skeldon and Dijk about our article Weekly, seasonal and chronotype-dependent variation of dim light melatonin ......

JIF:11.694

Melatonin treatment improves ventricular conduction via upregulation of Nav1.5 channel proteins and sodium current in the normal rat heart

期刊: JOURNAL OF PINEAL RESEARCH, 2022; 73 (1)

Melatonin treatment was reported to reduce the risk of cardiac arrhythmias, and crucial for this antiarrhythmic action was the effect of melatonin on ......

JIF:11.694

The role of MEK1/2 and MEK5 in melatonin-mediated actions on osteoblastogenesis, osteoclastogenesis, bone microarchitecture, biomechanics, and bone formation

期刊: JOURNAL OF PINEAL RESEARCH, 2022; 73 (2)

Melatonin, the primary hormone involved in circadian entrainment, plays a significant role in bone physiology. This study aimed to assess the role of ......

JIF:11.694

Sini powder with paroxetine ameliorates major depressive disorder by modulating circadian rhythm: A randomized, double-blind, placebo-controlled trial

期刊: JOURNAL OF PINEAL RESEARCH, 2022; 73 (4)

Circadian rhythm disorder is a significant risk factor for mental diseases, and the recovery of circadian rhythm function has gradually become a signa......

JIF:11.694

Tunneling nanotubes and mesenchymal stem cells: New insights into the role of melatonin in neuronal recovery

期刊: JOURNAL OF PINEAL RESEARCH, 2022; 73 (1)

Efficient cell-to-cell communication is essential for tissue development, homeostasis, and the maintenance of cellular functions after injury. Tunneli......

JIF:11.694

Effects of dynamic lighting on circadian phase, self-reported sleep and performance during a 45-day space analog mission with chronic variable sleep deficiency

期刊: JOURNAL OF PINEAL RESEARCH, 2022; 73 (4)

Spaceflight exposes crewmembers to circadian misalignment and sleep loss, which impair cognition and increase the risk of errors and accidents. We com......

JIF:11.694

Fine-tuning of pathogenesis-related protein 1 (PR1) activity by the melatonin biosynthetic enzyme ASMT2 in defense response to cassava bacterial blight

期刊: JOURNAL OF PINEAL RESEARCH, 2022; 72 (2)

Melatonin is widely involved in plant disease resistance through modulation of immune responses. Pathogenesis-related (PR) proteins play important rol......

JIF:11.694

The phytomelatonin receptor PMTR1 regulates seed development and germination by modulating abscisic acid homeostasis in Arabidopsis thaliana

期刊: JOURNAL OF PINEAL RESEARCH, 2022; 72 (4)

Melatonin is known to involve multiple physiological actions in plants. Herein, we found that exogenous melatonin inhibited the Arabidopsis seedling g......

JIF:11.694

Melatonin and andrographolide synergize to inhibit the colospheroid phenotype by targeting Wnt/beta-catenin signaling

期刊: JOURNAL OF PINEAL RESEARCH, 2022; 73 (1)

beta-catenin signaling, and angiogenesis are associated with colospheroid (CSC), development. CSCs, spheroids derived from colon cancer cells, are res......

JIF:11.694

Melatonin alleviates PM2.5-induced glucose metabolism disorder and lipidome alteration by regulating endoplasmic reticulum stress

期刊: JOURNAL OF PINEAL RESEARCH, 2022; 73 (4)

Exposure to fine particulate matter (PM2.5) was associated with an increased incidence of liver metabolic disease. Melatonin has been shown to prevent......

JIF:11.694

Recharge of chondrocyte mitochondria by sustained release of melatonin protects cartilage matrix homeostasis in osteoarthritis

期刊: JOURNAL OF PINEAL RESEARCH, 2022; 73 (2)

Recent evidence indicates that the mitochondrial functions of chondrocytes are impaired in the pathogenesis of osteoarthritis (OA). Melatonin can atte......

JIF:11.694

Daytime rest: Association with 24-h rest-activity cycles, circadian timing and cognition in older adults

期刊: JOURNAL OF PINEAL RESEARCH, 2022; 73 (3)

Growing epidemiological evidence points toward an association between fragmented 24-h rest-activity cycles and cognition in the aged. Alterations in t......

JIF:11.694

High dose melatonin increases sleep duration during nighttime and daytime sleep episodes in older adults

期刊: JOURNAL OF PINEAL RESEARCH, 2022; 73 (1)

Aging is associated with changes in sleep, and improving sleep may have important consequences for the health, cognition, and quality of life of older......

JIF:11.694

Three months of melatonin treatment reduces insulin sensitivity in patients with type 2 diabetes-A randomized placebo-controlled crossover trial

期刊: JOURNAL OF PINEAL RESEARCH, 2022; 73 (1)

The use of the sleep-promoting hormone melatonin is rapidly increasing as an assumed safe sleep aid. During the last decade, accumulating observations......

JIF:11.694

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