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Association of serum vitamin D levels and TaqIrs731236 among patients with hypertensive coronary heart disease

期刊: STEROIDS, 2023; 191 ()

The development of cardiovascular diseases (CVD) is influenced through multiple risk factor and hypertension. It may increase the risk of cardiac even......

The combined effects of treadmill exercise and steroid administration on anterior cruciate ligament reconstruction-induced joint contracture and muscle atrophy in rats

期刊: STEROIDS, 2023; 192 ()

Rehabilitation protocols to treat joint contracture and muscle atrophy following anterior cruciate ligament (ACL) reconstruction have not been establi......

Dexamethasone induces cancer mitigation and irreversible senescence in lung cancer cells via damaging cortical actin and sustained hyperphosphorylation of pRb

期刊: STEROIDS, 2023; 198 ()

Activation of the glucocorticoid receptors by its cognate ligand, dexamethasone (DEX) is commonly used as an adjuvant treatment in solid tumors. Howev......

Corticosterone rapidly reduces glutamatergic but not GABAergic transmission in the infralimbic prefrontal cortex of male mice

期刊: STEROIDS, 2023; 198 ()

Rapid non-genomic effects of corticosteroid hormones, affecting glutamatergic and GABAergic transmission, have been described for many limbic structur......

Adverse cognitive effects of glucocorticoids: A systematic review of the literature

期刊: STEROIDS, 2023; 200 ()

Objectives: Glucocorticoids as a drug class are widely used in the treatment of many conditions including more recently as one of the mainstay treatme......

Chenodeoxycholic acid regulates fibroblast growth factor 23 gene expression via estrogen-related receptor γ in human hepatoma Huh7 cells

期刊: STEROIDS, 2023; 197 ()

Fibroblast growth factor 23 (FGF23) is a glycoprotein that belongs to the FGF19 subfamily and participates in phosphate and vitamin D homeostasis. Che......

Seasonal AMH variability implies a positive effect of UV exposure on the deterioration of ovarian follicles

期刊: STEROIDS, 2023; 200 ()

Anti-Mullerian hormone (AMH) is produced exclusively by granulosa cells of ovarian follicles and is an indicator of ovarian reserve which declines wit......

In silico ADMET analysis of the A-, B- and D-modified androstane derivatives with potential anticancer effects

期刊: STEROIDS, 2023; 189 ()

The major challenge in the fight against cancer is to design new drugs that will be more selective for cancer cells, with fewer side effects. Syntheti......

Systemic corticosteroid use and cardiovascular risk in patients hospitalized for pneumonia

期刊: STEROIDS, 2023; 191 ()

Background: Limited data are available concerning cardiovascular risk with respect to adjunctive corticosteroid use in patients with pneumonia. We aim......

Anticholinesterase and anti-inflammatory constituents from Caralluma awdeliana, a medicinal plant from Yemen

期刊: STEROIDS, 2023; 193 ()

From the dichloromethane (DCM) fraction of the crude ethanolic extract of Caralluma awdeliana, four pregnane glycosides and a flavone glycoside were i......

Long-term exposure to high-concentration dexamethasone in the inner ear via intratympanic administration

期刊: STEROIDS, 2023; 189 ()

The first-line treatment for inner ear disorders is usually oral/systemic steroids. Intratympanic steroid therapy is an alternative option; however, i......

Methyl esters of 23,24-Dinor-5α-cholan-22-oic acids as brassinosteroid Analogues. Synthesis, evaluation of plant growth promoting activity and Molecular docking

期刊: STEROIDS, 2023; 196 ()

Five new brassinosteroid analogues were synthetized from 38-acetoxy-23,24-dinorchol-4-en-22-oic acid. All the obtained compound showed significant act......

Fast signaling by glucocorticoids shapes neural representations of behaviors

期刊: STEROIDS, 2023; 199 ()

Glucocorticoids are stress hormones that play central roles in the immediate and slower adaptive responses of the brain and body to new behavioral exp......

Synthesis of fully functionalized spirostanic 1,2,3-triazoles by the three component reaction of diosgenin azides with acetophenones and aryl aldehydes and their biological evaluation as antiproliferative agents

期刊: STEROIDS, 2023; 190 ()

Diosgenin is of significant interest due to its biological activity and synthetic application. In this study, we report the synthesis of a series of s......

Reduction of seizures and inflammatory markers by betamethasone in a kindling seizure model

期刊: STEROIDS, 2023; 193 ()

Epilepsy is a chronic disease characterized by an ongoing predisposition to seizures. Although inflammation has emerged as a crucial factor in the eti......

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