期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (23)
Enhancers activate their cognate promoters over huge distances but how enhancer/promoter interactions become established is not completely understood.......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (5)
Due to unique features, proline residues may control protein structure and function. Here, we investigated the role of 52PPQ54 residues, indicated by ......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (12)
Pathogenic mutations in the leucine-rich repeat kinase 2 (LRRK2) gene hyperactivate LRRK2 kinase activity and lead to the development of Parkinson's d......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (14)
Prediction of orthologs is an important bioinformatics pursuit that is frequently used for inferring protein function and evolutionary analyses. The I......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (8)
The detection of structural chromosomal abnormalities (SCA) is crucial for diagnosis, prognosis and man-agement of many genetic diseases and cancers. ......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (12)
Neurodegenerative diseases, such as Alzheimer's and Parkinson's, are characterized by several patho-logical features, including selective neuronal los......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (16)
The cellular defense against viruses involves the assembly of oligomers, granules and membraneless organelles (MLOs) that govern the activation of sev......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (21)
Polymorphic toxins (PTs) are a broad family of toxins involved in interbacterial competition and pathogenesis. PTs are modular proteins that are compr......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (2)
Barrier-to-Autointegration Factor (BAF) is a highly conserved DNA binding protein important for genome integrity. Its localization and function are re......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (5)
Eukaryotic translation initiation factor 4E (eIF4E) is a key factor involved in different aspects of mRNA metabolism. Drosophila melanogaster genome e......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (10)
The neuronal SNARE protein SNAP25a (isoform 2) forms part of the SNARE complex eliciting synaptic vesicle fusion during neuronal exocytosis. While the......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (11)
Functional amyloids are a rapidly expanding class of fibrillar protein structures, with a core cross-0 scaffold, where novel and advantageous biologic......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (14)
Operons are groups of consecutive genes that transcribe together under the regulation of a common promoter. They influence protein regulation and vari......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (12)
Sphingolipids, including the basic ceramide, are a subset of bioactive lipids that consist of many different species. Sphingolipids are indispensable ......
期刊： JOURNAL OF MOLECULAR BIOLOGY, 2023; 435 (14)
G protein coupled receptors (GPCRs) are critical eukaryotic signal transduction gatekeepers and repre-sent the largest protein superfamily in the huma......
