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Polymorphisms in TYMS for Prediction of Capecitabine-Induced Hand-Foot Syndrome in Chinese Patients with Colorectal Cancer

期刊: CANCER RESEARCH AND TREATMENT, 2021; 53 (3)

Purpose Capecitabine is an extensively used oral prodrug of 5-fluorouracil in treatment of colon cancer and is known to cause hand foot syndrome (HFS)......

The Pattern of Time to Onset and Resolution of Immune-Related Adverse Events Caused by Immune Checkpoint Inhibitors in Cancer: A Pooled Analysis of 23 Clinical Trials and 8,436 Patients

期刊: CANCER RESEARCH AND TREATMENT, 2021; 53 (2)

Purpose The occurrence pattern of immune-related adverse events (irAEs) induced by immune checkpoint inhibitor (ICI) in cancer treatment remains uncle......

Double Tract Reconstruction Reduces Reflux Esophagitis and Improves Quality of Life after Radical Proximal Gastrectomy for Patients with Upper Gastric or Esophagogastric Adenocarcinoma

期刊: CANCER RESEARCH AND TREATMENT, 2021; 53 (3)

Purpose The aim of the present study was to compare the difference between double tract reconstruction and esophagogastrostomy. Materials and Methods ......

A Case of Simultaneously Diagnosed Lung Adenocarcinoma and Endobronchial Inflammatory Myofibroblastic Tumor with Two Distinct Types of ALK Translocation

期刊: CANCER RESEARCH AND TREATMENT, 2021; 53 (2)

A 61-year-old male patient was simultaneously diagnosed with lung adenocarcinoma and inflammatory myofibroblastic tumor (IMT). The lung adenocarcinoma......

Identification of a Novel CSNK2A1-PDGFRB Fusion Gene in a Patient with Myeloid Neoplasm with Eosinophilia

期刊: CANCER RESEARCH AND TREATMENT, 2021; 53 (3)

Platelet-derived growth factor receptor beta (PDGFRB) rearrangements play an important role in the pathogenesis of eosinophiliaassociated myeloid/lymp......

Risk of Death in Colorectal Cancer Patients with Multi-morbidities of Metabolic Syndrome: A Retrospective Multicohort Analysis

期刊: CANCER RESEARCH AND TREATMENT, 2021; 53 (3)

Purpose The prevalence of multi-morbidities with colorectal cancer (CRC) is known to be increasing. Particularly prognosis of CRC patients co-diagnose......

Hepatitis B Virus Core Protein Mediates the Upregulation of C5? Receptor 1 via NF-KB Pathway to Facilitate the Growth and Migration of Hepatoma Cells

期刊: CANCER RESEARCH AND TREATMENT, 2021; 53 (2)

Purpose C5 alpha receptor 1 (C5 alpha R1) is associated with the development of various human cancers. However, whether it is involved in the developm......

Knockdown of EMMPRIN (OX47) in MRMT-1 Carcinoma Cells Inhibits Tumor Growth and Decreases Cancer-Induced Bone Destruction and Pain

期刊: CANCER RESEARCH AND TREATMENT, 2021; 53 (2)

Purpose Bone destruction and pain caused by cancer is one of the most devastating complications of cancer patients with bone metastases, and it seriou......

Upregulated N6-Methyladenosine RNA in Peripheral Blood: Potential Diagnostic Biomarker for Breast Cancer

期刊: CANCER RESEARCH AND TREATMENT, 2021; 53 (2)

Purpose An effective biomarker for the diagnosis of breast cancer (BC) and benign breast diseases (BBD) is crucial for improving the prognosis. We inv......

Comparison of the Prognostic Value of Platelet-Related Indices in Biliary Tract Cancer Undergoing Surgical Resection

期刊: CANCER RESEARCH AND TREATMENT, 2021; 53 (2)

Purpose Platelet-related indices, including mean platelet volume (MPV) and plateletocrit (PCT), have been reported as new prognostic factors of overal......

Mutant IDH1 Enhances Temozolomide Sensitivity via Regulation of the ATM/CHK2 Pathway in Glioma

期刊: CANCER RESEARCH AND TREATMENT, 2021; 53 (2)

Purpose Isocitrate dehydrogenase 1 (IDH1) mutations are the most common genetic abnormalities in low-grade gliomas and secondary glioblastomas. Glioma......

Development and Validation of Web-Based Nomograms to Precisely Predict Survival Outcomes of Non-metastatic Nasopharyngeal Carcinoma in an Endemic Area

期刊: CANCER RESEARCH AND TREATMENT, 2021; 53 (3)

Purpose This study aimed to develop web-based nomograms to precisely predict survival outcomes in patients with non-metastatic nasopharyngeal carcinom......

Cervical Cancer Screening Rate and Willingness among Female Migrants in Shenzhen, China: Three-Year Changes in Citywide Surveys

期刊: CANCER RESEARCH AND TREATMENT, 2021; 53 (1)

Purpose This study attempted to detect the changes of cervical cancer screening rate and willingness among female migrants, and the associated socio-d......

Long Non-coding RNA CASC15 Promotes Intrahepatic Cholangiocarcinoma Possibly through Inducing PRDX2/PI3K/AKT Axis

期刊: CANCER RESEARCH AND TREATMENT, 2021; 53 (1)

Purpose Intrahepatic cholangiocarcinoma (ICC) is one of the most common liver primary tumors but its treatments are limited. Bioinformatics showed tha......

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