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Elevated Hemoglobin A1c Is Associated With Leaky Plaque Neovasculature as Detected by Dynamic Contrast-Enhanced Magnetic Resonance Imaging

期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (4)

Background: Patients with diabetes have accelerated atherosclerosis progression, but the underlying mechanisms are not fully understood. Dynamic contr......

JIF:5.563

N6-Methyladenosine Demethylase FTO (Fat Mass and Obesity-Associated Protein) as a Novel Mediator of Statin Effects in Human Endothelial Cells

期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (5)

Background: N6-methyladenosine (m6A) plays a critical role in various biological processes. However, no study has addressed the role of m6A modificati......

JIF:5.563

Ambient Air Pollution and Atherosclerosis: A Potential Mediating Role of Sphingolipids

期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (7)

Background: The pathophysiological mechanisms of air pollution-induced atherosclerosis are incompletely understood. Sphingolipids serve as biological ......

JIF:5.563

Multi-Omics Signatures Link to Ticagrelor Effects on Vascular Function in Patients With Acute Coronary Syndrome

期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (6)

BACKGROUND: Long-term antiplatelet agents including the potent P2Y12 antagonist ticagrelor are indicated in patients with a previous history of acute ......

JIF:5.563

Single-Cell RNA Sequencing and Assay for Transposase-Accessible Chromatin Using Sequencing Reveals Cellular and Molecular Dynamics of Aortic Aging in Mice

期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (2)

Objective: The impact of vascular aging on cardiovascular diseases has been extensively studied; however, little is known regarding the cellular and m......

JIF:5.563

Endothelial Intracellular ANG (Angiogenin) Protects Against Atherosclerosis by Decreasing Endoplasmic Reticulum Stress

期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (3)

Background: ANG (angiogenin) is essential for cellular adaptation to endoplasmic reticulum (ER) stress, a process closely associated with cardiovascul......

JIF:5.563

Clock Gene Bmal1 Disruption in Vascular Smooth Muscle Cells Worsens Carotid Atherosclerotic Lesions

期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (5)

Background: Clock system disruptions are associated with cardiovascular diseases. We previously demonstrated Bmal1 (brain muscle aryl nuclear transloc......

JIF:5.563

Specific Loss of ABCA1 (ATP-Binding Cassette Transporter A1) Suppresses TCR (T-Cell Receptor) Signaling and Provides Protection Against Atherosclerosis

期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (12)

Background:ABCA1 (ATP-binding cassette transporter A1) mediates cholesterol efflux to apo AI to maintain cellular cholesterol homeostasis. The current......

JIF:5.563

Different Metabolic Phenotypes of Obesity and Risk of Coronary Artery Calcium Progression and Incident Cardiovascular Disease Events: The CARDIA Study

期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (5)

BACKGROUND: To investigate whether obesity with or without metabolic syndrome is prospectively associated with coronary artery calcium (CAC) progressi......

JIF:5.563

KANK4 Promotes Arteriogenesis by Potentiating VEGFR2 Signaling in a TALIN-1-Dependent Manner

期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (6)

Background: Arteriogenesis plays a critical role in maintaining adequate tissue blood supply and is related to a favorable prognosis in arterial occlu......

JIF:5.563

Single-Cell Transcriptome Analysis Reveals Embryonic Endothelial Heterogeneity at Spatiotemporal Level and Multifunctions of MicroRNA-126 in Mice

期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (3)

Background: Endothelial cells (ECs) play a critical role in angiogenesis and vascular remodeling. The heterogeneity of ECs has been reported at adult ......

JIF:5.563

Major Vault Protein Prevents Atherosclerotic Plaque Destabilization by Suppressing Macrophage ASK1-JNK Signaling

期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (5)

Background: Macrophages are implicated in atherosclerotic plaque instability by inflammation and degradation of extracellular matrix. However, the reg......

JIF:5.563

Long Noncoding RNA TPRG1-AS1 Suppresses Migration of Vascular Smooth Muscle Cells and Attenuates Atherogenesis via Interacting With MYH9 Protein

期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (11)

Background: Migration of human aortic smooth muscle cells (HASMCs) contributes to the pathogenesis of atherosclerosis. This study aims to functionally......

JIF:5.563

Caspase-8 Promotes Pulmonary Hypertension by Activating Macrophage-Associated Inflammation and IL-1 beta (Interleukin 1 beta) Production

期刊: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2022; 42 (5)

Background: Macrophages are involved in the pathogenesis of pulmonary arterial hypertension (PAH). Caspase-8, an apical component of cell death pathwa......

JIF:5.563

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