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Vascular smooth muscle cell-derived hydrogen sulfide promotes atherosclerotic plaque stability via TFEB (transcription factor EB)-mediated autophagy

期刊: AUTOPHAGY, 2022; 18 (10)

Vascular smooth muscle cells (VSMCs) contribute to plaque stability. VSMCs are also a major source of CTH (cystathionine gamma-lyase)-hydrogen sulfide......

JIF:8.531

Selective autophagy of NLRC5 promotes immune evasion of endometrial cancer

期刊: AUTOPHAGY, 2022; 18 (4)

Endometrial cancer (EC), the most common gynecological cancer, is usually resistant to chemotherapy when the EC patients are advanced or recurrent. Im......

JIF:8.531

Emerging views of OPTN (optineurin) function in the autophagic process associated with disease

期刊: AUTOPHAGY, 2022; 18 (1)

Macroautophagy/autophagy is a highly conserved process in eukaryotic cells. It plays a critical role in cellular homeostasis by delivering cytoplasmic......

JIF:8.531

Mycobacterium bovis induces mitophagy to suppress host xenophagy for its intracellular survival

期刊: AUTOPHAGY, 2022; 18 (6)

Mitophagy is a selective autophagy mechanism for eliminating damaged mitochondria and plays a crucial role in the immune evasion of some viruses and b......

JIF:8.531

Autophagy regulates differentiation of ovarian granulosa cells through degradation of WT1

期刊: AUTOPHAGY, 2022; 18 (8)

Ovarian granulosa cells (GCs) proliferate and differentiate along with follicular growth, and this is indispensable for oocyte development and female ......

JIF:8.531

A switch of chaperonin function regulates the clearance of solid protein aggregates

期刊: AUTOPHAGY, 2022; 18 (11)

Protein aggregation is related to many human diseases. Selective macroautophagy/autophagy is the major way to clear protein aggregates in eukaryotic c......

JIF:8.531

A conserved interplay between FOXO and SNAI/snail in autophagy

期刊: AUTOPHAGY, 2022; 18 (11)

Dysfunction of macroautophagy/autophagy has been implicated in homeostasis maintenance and contributes to various diseases. Yet the mechanisms that re......

JIF:8.531

Targeting MCOLN1/TRPML1 channels to protect against ischemia-reperfusion injury by restoring the inhibited autophagic flux in cardiomyocytes

期刊: AUTOPHAGY, 2022; 18 (12)

Accumulating evidence suggests that macroautophagy/autophagy dysfunction plays a critical role in myocardial ischemia-reperfusion (I/R) injury. Howeve......

JIF:8.531

m(6)A reader YTHDC1 modulates autophagy by targeting SQSTM1 in diabetic skin

期刊: AUTOPHAGY, 2022; 18 (6)

Dysregulation of macroautophagy/autophagy contributes to the delay of wound healing in diabetic skin. N-6-methyladenosine (m(6)A) RNA modification is ......

JIF:8.531

CAMK2/CaMKII activates MLKL in short-term starvation to facilitate autophagic flux

期刊: AUTOPHAGY, 2022; 18 (4)

MLKL (mixed lineage kinase domain like pseudokinase) is a well-known core component of necrosome that executes necroptotic cell death upon phosphoryla......

JIF:8.531

Extracellular vesicles originating from autophagy mediate an antibody-resistant spread of classical swine fever virus in cell culture

期刊: AUTOPHAGY, 2022; 18 (6)

Free spread is a classical mode for mammalian virus transmission. However, the efficiency of this transmission approach is generally low as there are ......

JIF:8.531

M05B5.4 (lysosomal phospholipase A2) promotes disintegration of autophagic vesicles to maintain C. elegans development

期刊: AUTOPHAGY, 2022; 18 (3)

The autophagosome has two lipid bilayer membranes. The outer membrane fuses with the lysosome, while the inner membrane is degraded to release autopha......

JIF:8.531

Rice black-streaked dwarf virus P10 promotes phosphorylation of GAPDH (glyceraldehyde-3-phosphate dehydrogenase) to induce autophagy in Laodelphax striatellus

期刊: AUTOPHAGY, 2022; 18 (4)

Macroautophagy/autophagy is an important innate and adaptive immune response that can clear microbial pathogens through guiding their degradation. Vir......

JIF:8.531

USP19 (ubiquitin specific peptidase 19) promotes TBK1 (TANK-binding kinase 1) degradation via chaperone-mediated autophagy

期刊: AUTOPHAGY, 2022; 18 (4)

TBK1 (TANK-binding kinase 1) is an essential receptor protein required for the innate immune response, but the mechanisms underlying TBK1 stability, e......

JIF:8.531

Identification of an autoinhibitory, mitophagy-inducing peptide derived from the transmembrane domain of USP30

期刊: AUTOPHAGY, 2022; 18 (9)

The mitochondrial-anchored deubiquitinating enzyme USP30 (ubiquitin specific peptidase 30) antagonizes PRKN/parkin-mediated mitophagy, making it a pot......

JIF:8.531

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