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Pathophysiology, phenotypes and management of type 2 diabetes mellitus in Indian and Chinese populations

期刊: NATURE REVIEWS ENDOCRINOLOGY, 2022; 18 (7)

Prevalence of type 2 diabetes mellitus (T2DM) is increasing substantially in India and China. This Review discusses the epidemiology, phenotypes and p......

JIF:10.388

Modelling metabolic diseases and drug response using stem cells and organoids

期刊: NATURE REVIEWS ENDOCRINOLOGY, 2022; 18 (12)

Organoids are a promising tool for modelling diseases in vitro. This Review discusses the progress in developing liver and adipose tissue organoids to......

JIF:10.388

The emerging role of incretins and twincretins

期刊: NATURE REVIEWS ENDOCRINOLOGY, 2022; 18 (2)

In 2021, clinical trials reported the promising effects of incretins and a new class of dual glucagon-like peptide 1-glucose-dependent insulinotropic ......

JIF:10.388

A road map for understanding molecular and genetic determinants of osteoporosis

期刊: NATURE REVIEWS ENDOCRINOLOGY, 2020; 16 (2)

Osteoporosis is a highly prevalent disorder characterized by low bone mineral density and an increased risk of fracture, termed osteoporotic fracture.......

The role of macrophages in obesity-associated islet inflammation and beta-cell abnormalities

期刊: NATURE REVIEWS ENDOCRINOLOGY, 2020; 16 (2)

Chronic, unresolved tissue inflammation is a well-described feature of obesity, type 2 diabetes mellitus (T2DM) and other insulin-resistant states. In......

Benefit of lifestyle-based T2DM prevention is influenced by prediabetes phenotype

期刊: NATURE REVIEWS ENDOCRINOLOGY, 2020; 16 (7)

The prevention of type 2 diabetes mellitus (T2DM) is a target priority for the WHO and the United Nations and is a key priority in the 2018 Berlin Dec......

Human sperm RNA code senses dietary sugar

期刊: NATURE REVIEWS ENDOCRINOLOGY, 2020; 16 (4)

A new study reveals that a high-sugar diet acutely alters human sperm small RNA profiles after 1 week and that these changes are associated with chang......

The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic

期刊: NATURE REVIEWS ENDOCRINOLOGY, 2020; 16 (11)

Fibroblast growth factor 21 (FGF21) confers considerable pharmacological benefits on a cluster of obesity-related metabolic complications when adminis......

The clinical potential of circulating microRNAs in obesity

期刊: NATURE REVIEWS ENDOCRINOLOGY, 2019; 15 (12)

Obesity is a complex condition that is characterized by excessive fat accumulation, which can lead to the development of metabolic disorders, such as ......

JIF:24.65

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