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Differential expression of serum miR-486 and miR-25 in ulcerative colitis and Crohn's disease: Correlations with disease activity, extent, and location

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 252 ()

Novel reliable biomarkers of inflammatory bowel disease (IBD) are clinically imperative due to potential limi-tations of endoscopic techniques. MicroR......

Direct specimen collection during routine operation improves nucleic acid quality in genetic analysis samples for head and neck tumors: A retrospective study

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 252 ()

The nucleic acid integrity of head and neck squamous cell carcinoma (HNSCC) samples is poor, and the material available for genetic analysis is limite......

Nazi persecutee and opponent of racial hygiene: The extraordinary life of the ethnopathologist Max Kuczynski (1890-1967)

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 252 ()

The pathologist Max Kuczynski (1890-1967) gained recognition for his bacteriological research but is also considered the founder of the so-called ethn......

The role of miRNAs in the pathogenesis and therapeutic resistance of endometrial cancer: a spotlight on the convergence of signaling pathways

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 244 ()

Endometrial cancer (EC) is the 2nd common cancer in females after breast cancer. Besides, it's the most common among gynecological cancers. Several ep......

Hypoxia-induced UBE2K promotes the malignant progression of HCC

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 245 ()

Background: Hypoxia critically drives malignant tumor development and is characteristic of hepatocellular carcinoma (HCC), where HIF-1 alpha plays a c......

Exosomes released from U87 glioma cells treated with curcumin and/or temozolomide produce apoptosis in naive U87 cells

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 245 ()

Glioblastoma (GBM) remains the most lethal brain tumor without any curative treatment. Exosomes can mediate cell-to-cell communication, and may functi......

Joint analysis identified FAP as a prognostic and diagnostic biomarker correlated immune infiltration in gastric cancer

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 245 ()

Gastric cancer is one of the most malignant types of cancer in the digestive system because of its high incidence and mortality. There is a notable as......

A review on the role of ZEB1-AS1 in human disorders

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 245 ()

ZEB1 Antisense RNA 1 (ZEB1-AS1) is a type of RNA characterized as long non-coding RNA (lncRNA). This lncRNA has important regulatory roles on its rela......

DNA aneuploidy identifies a subset of Luminal subtype breast carcinoma patients with worse clinical outcome

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 246 ()

Aim: In breast carcinoma (BC), the relationship between the ploidy pattern and molecular subtyping is still unknown. We aim to investigate the prognos......

The diagnostic and prognostic role of miR-27a in cancer

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 247 ()

MicroRNA-27a (miR-27a) has been reported to be abnormally expressed in patients with cancer, and it could play potential roles as a diagnostic and pro......

Roles of non-coding RNAs in cell death pathways involved in the treatment of resistance and recurrence of cancer

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 247 ()

Considering the burden of cancer, a number of methods have been applied to control or stop it. However, because of drug resistance or cancer recurrenc......

Highlighting functions of apoptosis and circular RNAs in colorectal cancer

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 248 ()

Colorectal cancer (CRC) is known as one of the global problems that endangers the lives of thousands of people every year. Various treatments have bee......

Relationship between the Warburg effect in tumour cells and the tumour microenvironment in colorectal cancer patients: Results from a large multicentre study

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 247 ()

Colorectal cancer (CRC) remains one of the most prevalent and deadly cancers worldwide. The tumour-nodemetastasis stage (TNM) is currently the most cl......

Non-coding RNAs and exosomal non-coding RNAs in pituitary adenoma

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 248 ()

Pituitary adenoma (PA) is the third most common primary intracranial tumor in terms of overall disease incidence. Although they are benign tumors, the......

Hypoxia inducible factor-1a (HIF-1a) in breast cancer: The crosstalk with oncogenic and onco-suppressor factors in regulation of cancer hallmarks

期刊: PATHOLOGY RESEARCH AND PRACTICE, 2023; 248 ()

Low oxygen level at tumor microenvironment leads to a condition, known as hypoxia that is implicated in cancer progression. Upon hypoxia, HIF-1a under......

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