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The Effect of Oral Vitamin A Supplementation on Chalazion in Young Children with Vitamin A Deficiency: A Pilot Study

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2021; 37 (6)

Purpose: Many researchers have reported that vitamin A (VA) deficiency is related to chalazion. The purpose of this article is to clarify the effects ......

Phospho-Sulindac (OXT-328) Inhibits Dry Eye Disease in Rabbits: A Dose-, Formulation- and Structure-Dependent Effect

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2021; 37 (6)

Purpose: Inflammation of the ocular surface is central to dry eye disease (DED). The anti-inflammatory agent phospho-sulindac (PS) at a high dose was ......

Novel Peptide NT/K-CRS Derived from Kringle Structure of Neurotrypsin Inhibits Neovascularization In Vitro and In Vivo

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2021; 37 (7)

Purpose: To assess the anti-neovascularization effect of a novel peptide NT/K-CRS derived from the kringle domain of neurotrypsin in vitro and in vivo......

Celastrol Regulates the Secretion of Interleukin-17 in Patients with Sympathetic Ophthalmia Through Signal Transducer and Activator of Transcription 3

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2021; 37 (6)

Purpose: The excessive secretion of interleukin (IL)-17 contributes to the pathological process of sympathetic ophthalmia (SO). Celastrol is a natural......

Surface Modification of Intraocular Lens with Hydrophilic Poly(Sulfobetaine Methacrylate) Brush for Posterior Capsular Opacification Prevention

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, ; ()

Purpose: The intraocular lens (IOL) is a common, yet important, implantable device used in treatment of cataract in clinics. However, the unexpected a......

Prognosis of Ocular Tuberculosis Following Long-Term Antitubercular Therapy

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, ; ()

Purpose: This study presents clinical features and prognosis after long-term (12-18 months) antitubercular therapy (ATT) in patients with ocular tuber......

The Effects of Antiglaucoma Ophthalmic Solutions on the Cornea Revealed by a Corneal Electrical Resistance Device

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2021; 37 (2)

Purpose: We sought to evaluate the effect of antiglaucoma ophthalmic solutions on the cornea with a corneal resistance device (CRD), and to compare th......

Intravitreal Conbercept Injection as an Adjuvant in Vitrectomy with Silicone Oil Infusion for Severe Proliferative Diabetic Retinopathy

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2020; 36 (5)

Purpose: To assess the clinical effects of preoperative, intraoperative, or preoperative combined with intraoperative intravitreal conbercept (IVC) in......

An UPLC-MS/MS Method for Simultaneous Determination of Tropicamide and Phenylephrine in Rabbit Ocular Tissues and Plasma

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2020; 36 (5)

Purpose: Mixed eye drops containing 0.5% tropicamide and 0.5% phenylephrine are commercially available for cycloplegic refraction. Determining the pha......

Analysis of Plasma Hydrogen Sulfide, Homocysteine, and L-Cysteine in Open-Angle Glaucoma Patients

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2020; 36 (8)

Purpose: To compare the plasma levels of hydrogen sulfide (H2S), homocysteine (Hcy), and L-cysteine (Cys) among primary open-angle glaucoma (POAG), no......

3-Methyladenine Alleviates Experimental Subretinal Fibrosis by Inhibiting Macrophages and M2 Polarization Through the PI3K/Akt Pathway

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2020; 36 (8)

Purpose:To explore the effects of 3-methyladenine (3-MA), a selective inhibitor of phosphatidylinositol-3-kinase (PI3K), on experimental subretinal fi......

Effect of the Antiglaucoma Agent JV-GL1 and Related Compounds in the Canine Eye

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2020; 36 (8)

Purpose:JV-GL1 is an efficacious, potent, and long-acting antiglaucoma agent, according to studies in ocular normotensive and hypertensive monkeys. As......

Nanomolar Potency Aminophenyltriazine CFTR Activator Reverses Corneal Epithelial Injury in a Mouse Model of Dry Eye

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2020; 36 (3)

Purpose: Dry eye disorders are a major health care burden. We previously reported the identification of N-methyl-N-phenyl-6-(2,2,3,3-tetrafluoropropox......

Celastrol Ameliorates Inflammation in Human Retinal Pigment Epithelial Cells by Suppressing NF-kappa B Signaling

期刊: JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2019; 35 (2)

Purpose: Celastrol is a triterpenoid quinine methide that exerts important biological effects on a variety of disease models. In this study, we aim to......

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