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Pulmonary Artery Smooth Muscle Cell Senescence Promotes the Proliferation of PASMCs by Paracrine IL-6 in Hypoxia-Induced Pulmonary Hypertension

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

Pulmonary hypertension (PH) is a critical and dangerous disease in cardiovascular system. Pulmonary vascular remodeling is an important pathophysiolog......

Serum Creatinine-to-Cystatin C Ratio in the Progression Monitoring of Non-alcoholic Fatty Liver Disease

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

Background The simultaneous assessment of visceral adiposity and muscle mass might be useful to monitor the risk of non-alcoholic fatty liver disease ......

Revascularization After Traumatic Spinal Cord Injury

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

Traumatic spinal cord injury (SCI) is a complex pathological process. The initial mechanical damage is followed by a progressive secondary injury casc......

Pathophysiologic Role of Neurotransmitters in Digestive Diseases

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

Neurotransmitters are special molecules that serve as messengers in chemical synapses between neurons, cells, or receptors, including catecholamines, ......

Comparison of Digestive Enzyme Activities and Expression of Small Intestinal Transporter Genes in Jinhua and Landrace Pigs

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

Digestive enzyme activity is involved in the regulation of growth performance because digestive enzymes function to improve the feed efficiency by dig......

Function and Mechanism of Trimetazidine in Myocardial Infarction-Induced Myocardial Energy Metabolism Disorder Through the SIRT1-AMPK Pathway

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

Myocardial energy metabolism (MEM) is an important factor of myocardial injury. Trimetazidine (TMZ) provides protection against myocardial ischemia/re......

On the Optimization of a Centrifugal Maglev Blood Pump Through Design Variations

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

Centrifugal blood pumps are usually designed with secondary flow paths to avoid flow dead zones and reduce the risk of thrombosis. Due to the secondar......

Regulation of the Autonomic Nervous System on Intestine

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

Intestine is composed of various types of cells including absorptive epithelial cells, goblet cells, endocrine cells, Paneth cells, immunological cell......

Genome-Wide Association Study of Vascular Bundle-Related Traits in Maize Stalk

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

The vascular bundle plays an important role in nutrient transportation in plants and exerts great influence on crop yield. Maize is widely used for fo......

Physical Exercise: An Overview of Benefits From Psychological Level to Genetics and Beyond

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

Any form of physical activity, including exercise, is linked with preventing several diseases including metabolic disorders, cancer, and mood disorder......

c-Jun Amino Terminal Kinase Signaling Promotes Aristolochic Acid-Induced Acute Kidney Injury

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

Aristolochic acid (AA) is a toxin that induces DNA damage in tubular epithelial cells of the kidney and is the cause of Balkan Nephropathy and Chinese......

Absence of Rgs5 Influences the Spatial and Temporal Fluctuation of Cardiac Repolarization in Mice

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

Aims This study investigated the contribution of the regulator of G-protein signaling 5 (Rgs5) knockout to the alteration of the action potential dura......

MicroRNA-29c Acting on FOS Plays a Significant Role in Nonalcoholic Steatohepatitis Through the Interleukin-17 Signaling Pathway

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

Nonalcoholic fatty liver disease is the most common hepatic disease in western countries and is even more ubiquitous in Asian countries. Our study det......

D-Galactose Induces Chronic Oxidative Stress and Alters Gut Microbiota in Weaned Piglets

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

Oxidative stress commonly occurs in pig production, which can severely damage the intestinal function of weaned piglets. This study was conducted to i......

Effects of Non-directional Mechanical Trauma on Gastrointestinal Tract Injury in Rats

期刊: FRONTIERS IN PHYSIOLOGY, 2021; 12 ()

Mechanical trauma can (MT) cause secondary injury, such as cardiomyocyte apoptosis and cardiac dysfunction has been reported. However, the effects of ......

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