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The role of SOCS proteins in the development of virus- induced hepatocellular carcinoma

期刊: VIROLOGY JOURNAL, 2021; 18 (1)

BackgroundLiver cancer has become one of the most common cancers and has a high mortality rate. Hepatocellular carcinoma is one of the most common liv......

A hSCARB2-transgenic mouse model for Coxsackievirus A16 pathogenesis

期刊: VIROLOGY JOURNAL, 2021; 18 (1)

Background Coxsackievirus A16 (CA16) is one of the neurotropic pathogen that has been associated with severe neurological forms of hand, foot, and mou......

Efficacy and safety of ledipasvir/sofosbuvir for hepatitis C among drug users: a systematic review and meta-analysis

期刊: VIROLOGY JOURNAL, 2021; 18 (1)

Background and aims Limited data is available on the efficacy of direct acting anti-viral drugs on hepatitis C in drug users. The aim of this meta-ana......

Construction of an infectious clone of Zika virus stably expressing an EGFP marker in a eukaryotic expression system

期刊: VIROLOGY JOURNAL, 2021; 18 (1)

Background Zika virus is becoming one of the most widely transmitted arboviruses in the world. Development of antiviral inhibitor and vaccine requires......

Impact of COVID-19 pandemic on the prevalence of respiratory viruses in children with lower respiratory tract infections in China

期刊: VIROLOGY JOURNAL, 2021; 18 (1)

Background The multifaceted non-pharmaceutical interventions (NPIs) taken during the COVID-19 pandemic not only decrease the spreading of the SARS-CoV......

A multiplex real-time PCR quantitation of human herpesvirus-6, 7, 8 viruses: application in blood transfusions

期刊: VIROLOGY JOURNAL, 2021; 18 (1)

BackgroundIn recent years, fluorescent quantitative polymerase chain reaction assays for detecting viral DNA are in widespread use throughout the worl......

Temporal phylogeny and molecular characterization of echovirus 30 associated with aseptic meningitis outbreaks in China

期刊: VIROLOGY JOURNAL, 2021; 18 (1)

BackgroundAn outbreak of aseptic meningitis occurred from June to August 2016, in Inner Mongolia Autonomous Region, China.MethodsTo determine its epid......

Packaging signal of influenza A virus

期刊: VIROLOGY JOURNAL, 2021; 18 (1)

Influenza A virus (IAV) contains a genome with eight single-stranded, negative-sense RNA segments that encode 17 proteins. During its assembly, all ei......

Antiviral Activities of a Medicinal Plant Extract Against Sacbrood Virus in Honeybees

期刊: VIROLOGY JOURNAL, 2021; 18 (1)

Background Sacbrood is an infectious disease of the honey bee caused by Scbrood virus (SBV) which belongs to the family Iflaviridae and is especially ......

Impact of the N501Y substitution of SARS-CoV-2 Spike on neutralizing monoclonal antibodies targeting diverse epitopes

期刊: VIROLOGY JOURNAL, 2021; 18 (1)

The emergence and rapid spread of the B.1.1.7 lineage (VOC-202012/01) SARS-CoV-2 variant has aroused global concern. The N501Y substitution is the onl......

Viral loads, lymphocyte subsets and cytokines in asymptomatic, mildly and critical symptomatic patients with SARS-CoV-2 infection: a retrospective study

期刊: VIROLOGY JOURNAL, 2021; 18 (1)

Background Tens of million cases of coronavirus disease-2019 (COVID-19) have occurred globally. The severe acute respiratory syndrome coronavirus 2 (S......

Genetic diversity and epidemiology of human rhinovirus among children with severe acute respiratory tract infection in Guangzhou, China

期刊: VIROLOGY JOURNAL, 2021; 18 (1)

Background Human rhinovirus (HRV) is one of the major viruses of acute respiratory tract disease among infants and young children. This work aimed to ......

Transmitted drug resistance and transmission clusters among HIV-1 treatment-naive patients in Guangdong, China: a cross-sectional study

期刊: VIROLOGY JOURNAL, 2021; 18 (1)

Background Transmitted drug resistance (TDR) that affects the effectiveness of the first-line antiretroviral therapy (ART) regimen is becoming prevale......

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