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A review of dementia, focusing on the distinct roles of viral protein corona and MMP9 in dementia: Potential pharmacotherapeutic priorities

期刊: AGEING RESEARCH REVIEWS, 2022; 75 ()

Dementia, in particular, is a defining feature of Alzheimer's and Parkinson's diseases. Because of the combination of motor and cognitive impairments,......

JIF:10.078

Do Vitamin D receptor gene polymorphisms affect bone mass density in men?: A meta-analysis of observational studies

期刊: AGEING RESEARCH REVIEWS, 2022; 75 ()

The signs of aging in humans can often be detected through a decrease in bone mass density (BMD). The decrease in BMD as a risk of osteoporosis is oft......

JIF:10.078

Optimal dose and type of exercise to improve cognitive function in older adults: A systematic review and bayesian model-based network meta-analysis of RCTs

期刊: AGEING RESEARCH REVIEWS, 2022; 76 ()

Objective: To examine the dose-response relationship between overall and specific types of exercise with cognitive function in older adults. Design: S......

JIF:10.078

Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity

期刊: AGEING RESEARCH REVIEWS, 2022; 78 ()

Life expectancy has increased substantially over the last 150 years. Yet this means that now most people also spend a greater length of time suffering......

JIF:10.078

A new generation of AD biomarkers: 2019 to 2021

期刊: AGEING RESEARCH REVIEWS, 2022; 79 ()

Alzheimer's disease (AD) is the most common form of dementia and cases are rising worldwide. The effort to fight this disease is hampered by a lack of......

JIF:10.078

The hallmarks of aging in Ataxia-Telangiectasia

期刊: AGEING RESEARCH REVIEWS, 2022; 79 ()

Ataxia-telangiectasia (A-T) is caused by absence of the catalytic activity of ATM, a protein kinase that plays a central role in the DNA damage respon......

JIF:10.078

Deciphering clock genes as emerging targets against aging

期刊: AGEING RESEARCH REVIEWS, 2022; 81 ()

The old people often suffer from circadian rhythm disturbances, which in turn accelerate aging. Many agingrelated degenerative diseases such as Alzhei......

JIF:10.078

Ventricular arrhythmias in acute myocardial ischaemia-Focus on the ageing and sex

期刊: AGEING RESEARCH REVIEWS, 2022; 81 ()

Annually, approximately 17 million people die from cardiovascular diseases worldwide, half of them suddenly. The most common direct cause of sudden ca......

JIF:10.078

Psychometric characteristics of comprehensive geriatric assessments (CGAs) for long-term care facilities and community care: A systematic review

期刊: AGEING RESEARCH REVIEWS, 2022; 81 ()

Background: Comprehensive Geriatric Assessments (CGAs) have been incorporated as an integrated care approach effective to face the challenges associat......

JIF:10.078

Potential mechanisms underlying the accelerated cognitive decline in people with chronic low back pain: A scoping review

期刊: AGEING RESEARCH REVIEWS, 2022; 82 ()

A growing body of evidence has shown that people with chronic low back pain (CLBP) demonstrate significantly greater declines in multiple cognitive do......

JIF:10.078

Innate immunity dysregulation in aging eye and therapeutic interventions

期刊: AGEING RESEARCH REVIEWS, 2022; 82 ()

The prevalence of eye diseases increases considerably with age, resulting in significant vision impairment. Although the pathobiology of age-related e......

JIF:10.078

Frailty and pain, human studies and animal models

期刊: AGEING RESEARCH REVIEWS, 2022; 73 ()

The hypothesis that pain can predispose to frailty development has been recently investigated in several clinical studies suggesting that frailty and ......

JIF:10.078

Promise of irisin to attenuate cognitive dysfunction in aging and Alzheimer's disease

期刊: AGEING RESEARCH REVIEWS, 2022; 78 ()

Strategies proficient for relieving cognitive impairments in aging and Alzheimer's disease (AD) have an enor-mous impact. Regular physical exercise (P......

JIF:10.078

Neurogenesis in aging and age-related neurodegenerative diseases

期刊: AGEING RESEARCH REVIEWS, 2022; 78 ()

Adult neurogenesis, the process by which neurons are generated in certain areas of the adult brain, declines in an age-dependent manner and is one pot......

JIF:10.078

Assessment of functional roles and therapeutic potential of integrin receptors in osteoarthritis: A systematic review and meta-analysis of preclinical studies

期刊: AGEING RESEARCH REVIEWS, 2022; 81 ()

Background: Integrins are heterodimeric transmembrane receptors that mediate a variety of biological function and plays a critical role in osteoarthri......

JIF:10.078

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