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An update on immunotoxicity and mechanisms of action of six environmental mycotoxins

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 163 ()

Paradoxically, aflatoxin B1 (AFB1), ochratoxin A (OTA), deoxynivalenol (DON), T-2 toxin (T-2), fumonisin B1 (FB1), and zearalenone (ZEA) have both imm......

JIF:4.399

Ultrasensitive electrochemical sensor for detection of rutin antioxidant by layered Ti3Al0.5Cu0.5C2 MAX phase

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 164 ()

MAX phases have attracted great attention due to unique features such as thermal and electrical conductivity, easy fabrication, heat resistant, and li......

JIF:4.399

Di-2-ethylhexyl phthalate (DEHP) induced lipid metabolism disorder in liver via activating the LXR/SREBP-1c/PPARa/? and NF-?B signaling pathway

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 165 ()

Di-2-ethylhexyl phthalate (DEHP) has been widely used in many fields (agricultural products, medical instruments, and food packing). As an environment......

JIF:4.399

Chronic lead exposure exacerbates hepatic glucolipid metabolism disorder and gut microbiota dysbiosis in high-fat-diet mice

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 170 ()

Lead (Pb) and obesity are co-occurring risk factors for metabolic disorders. However, there is still a lack of study on the combined effects of both s......

JIF:4.399

Evaluation of the impact of transgenic maize BT799 on growth, development and reproductive function of Sprague-Dawley rats in three generations

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 160 ()

BT799 was Bacillus thuringiensis-genetic modified (GM) maize, and Sprague-Dawley (SD) rats were treated with different diet formulations containing BT......

JIF:4.399

Umbelliferone delays the progression of diabetic nephropathy by inhibiting ferroptosis through activation of the Nrf-2/HO-1 pathway

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 163 ()

Background: Ferroptosis is a novel form of lipid reactive oxygen species and iron dependent cell death, and it has been shown to be involved in renal ......

JIF:4.399

Exposure assessment of urinary deoxynivalenol in pregnant women in Wuhan, China

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 167 ()

Deoxynivalenol (DON) is a ubiquitous trichothecene mycotoxin in food. DON and its modified forms can cross the placental barrier and influence the foe......

JIF:4.399

Chlorinated organophosphorus flame retardants-induced mitochondrial abnormalities and the correlation with progesterone production in mLTC-1 cells

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 169 ()

Environmental monitoring data have indicated that three chlorinated organophosphorus flame retardants (Cl-OPFRs), including tris(2-chloroethyl)-phosph......

JIF:4.399

Maternal exposure to polystyrene nanoplastics during gestation and lactation induces hepatic and testicular toxicity in male mouse offspring

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 160 ()

Nanoplastics have raised considerable concerns since their ubiquity in the environment and potential hazard to health. It has been proven that polysty......

JIF:4.399

Screen-printing of core-shell Mn3O4@C nanocubes based sensing microchip performing ultrasensitive recognition of allura red

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 162 ()

Allura red (AR) is a member of azo dyes is commonly used as an additive in foods and soft drinks. However, due to the special harm of the azo structur......

JIF:4.399

Maternal exposure to bis(2-ethylhexyl) phthalate during the thyroid hormone-dependent stage induces persistent emotional and cognitive impairment in middle-aged offspring mice

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 163 ()

Prenatal DEHP exposure can cause offspring neurodevelopmental toxicity, but the persistent effects of such exposure window are unclear. This study aim......

JIF:4.399

Current status of electrochemical detection of sunset yellow based on bibliometrics

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 164 ()

Sunset yellow is a synthetic azo colorant widely used in food and beverages. Excessive consumption of sunset yellow can lead to health risks, so it is......

JIF:4.399

A time-course study of microglial activation and dopaminergic neuron loss in the substantia nigra of mice with paraquat-induced Parkinson's disease

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 164 ()

Activated microglia play an active role in the pathogenesis of PD and paraquat (PQ) induces PD. The study was to understand the time relationship betw......

JIF:4.399

Fumonisin B1 induced intestinal epithelial barrier damage through endoplasmic reticulum stress triggered by the ceramide synthase 2 depletion

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 166 ()

Fumonisin B-1 (FB1) contamination in feed is of great concern nowadays. The intestine would be the first line when FB1-contaminated food or feed was i......

JIF:4.399

Oral toxicity evaluation of genetically modified lactic acid bacteria in three generations of Sprague Dawley rats

期刊: FOOD AND CHEMICAL TOXICOLOGY, 2022; 167 ()

Genetic modification has great advantages in improving performance of bacteria, but its oral safety has not been systematically evaluated. In this stu......

JIF:4.399

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